目前尚无专门针对TKI-ILD的影像学分类标准,但可参考美国临床协会(American Clinical Association)的免疫治疗相关不良事件中的肺不良反应分级:G1:局限于单个肺叶或<25%的肺实质;G2:累及1个以上肺叶或25%~50%的肺实质;G3:累及所有肺叶或50%的肺实质;G4:危及生命的呼吸功能衰竭,需要紧急干预(如插管或气管切开)[16...
RESULTS & CONCLUSIONS Compared with domestic clinical guidelines,foreign clinical guidelines included an additional COPD triple preparation,while involving fewer types of expectorants and antioxidants;there were only 12 kinds of COPD treatment drugs included in the WHO standard list of essential medicine,...
87. Castro M, Rubin AS, Laviolette M, et al. Effectiveness and safety of bronchial thermoplasty in the treatmentof severe asthma: a multicenter, randomized, double-blind, sham-controlled clinical trial. Am J Respir CritCare Med 2010; 181: 116–124. 88. Sun Q, Fang L, Roth M, et al....
Methods:Systematic review and IPD-MA will be conducted according to Preferred Reporting Items for a Systematic Review and Meta-Analyses IPD guidelines. Electronic databases (PubMed, Web of Science, EMBASE, Cochrane Central Register of Controlled Trials, ClinicalTrials.gov, OpenGrey and BioRxiv/MedRx...
LC-COPD患者免疫治疗适应证仍遵循美国国家癌症综合网络(National Comprehensive Cancer Network, NCCN)、美国临床肿瘤学会(American Society of Clinical Oncology, ASCO)等发布的指南。 ICIs可以刺激淋巴细胞杀伤肿瘤细胞。一些研究评估了ICIs的...
Clinical guidelines indicate that a chronic obstructive pulmonary disease (COPD) diagnosis is made from a single spirometry test. However, long-term stability of diagnosis based on forced expiratory volume in 1 s over forced vital capacity (FEV1/FVC)
Update on clinical aspects of chronic obstructive pulmonary disease. N Engl J Med. 2019;381(13):1257–66. https://doi.org/10.1056/NEJMra1900500. Article PubMed CAS Google Scholar Soler-Cataluña JJ, Piñera P, Trigueros JA, et al. Spanish COPD guidelines (GesEPOC) 2021 update. ...
Clinical guidelines for COPD will continue to evolve, driven by factors that include the effects of climate change on air quality and the long-term effects of respiratory viral infections, including SARS-CoV-2. Future versions of GOLD will likely have evidence-based recommendations that include the...
The disease has no clear diagnostic or therapeutic guidelines, thereby making both diagnosis and treatment challenging. Though a number of studies on ACO have been documented, gaps in knowledge regarding the pathophysiologic mechanism of this disorder exist. Addressing this issue is an urgent need for...
Vitamin D Guidelines in Primary Care April 23, 2025 Select Your InterestsJAMA Content Home New Online Current Issue Podcasts Coronavirus (COVID-19) Q&A Clinical Reviews Editors' Summary Medical News Author Interviews JAMAevidence: JAMA Guide to Statistics and Methods JAMAevidence: The Rational Cl...