The abundant serum protein alpha-1 antitrypsin (AAT) is the prototype chronic obstructive pulmonary disease (COPD) biomarker. AAT is an antiprotease which inhibits neutrophilderived proteases and protects the fragile tissues of the lung. Absence of this key antiprotease renders t...
INTRODUCTION: Alpha-1-antitrypsin deficiency (AATD) is an orphan disease that predisposes individuals to COPD and liver disease. The following is a comprehensive review of AATD from epidemiology to treatment for physicians who treat COPD or asthma. Areas covered: In this comprehensive rev...
Learn about genetic COPD and order a free AlphaID At Home Saliva Collection Kit to find out your risk for genetic COPD, or alpha-1 antitrypsin deficiency (AATD).
COPD 慢性阻塞性肺病 Chronic obstructive pulmonary disease (COPD) is airflow limitation caused by an inflammatory response to inhaled toxins, often cigarette smoke. Alpha-1 antitrypsin deficiency and various occupational exposures are less common causes in nonsmokers. Sy...
Learn about genetic COPD and order a free AlphaID At Home Saliva Collection Kit to find out your risk for genetic COPD, or alpha-1 antitrypsin deficiency (AATD).
Learn about genetic COPD and order a free AlphaID At Home Saliva Collection Kit to find out your risk for genetic COPD, or alpha-1 antitrypsin deficiency (AATD).
Learn about genetic COPD and order a free AlphaID At Home Saliva Collection Kit to find out your risk for genetic COPD, or alpha-1 antitrypsin deficiency (AATD).
Deficiency of alpha-1 antitrypsin increases the risk of developing COPD and other conditions that affect a range of bodily systems. 3.只有老年人才会患上COPD 3. Only older adults develop COPD COPD在老年人中当然比在年轻人中更常见,但年轻人并不能对这种疾病免疫。
Alpha-1-antitrypsin Deficiency This is a rare genetic condition caused by the lack of a protein called Alpha-1 antitrypsin (AAT). This protein normally protects the lungs from damage. A deficiency results in breathing difficulties from emphysema. Diagnosis of AAT deficiency is made through a simpl...
Alpha-1 antitrypsin deficiency EMPs: Endothelial microparticles NE: Neutrophil elastase TNF: Tumor necrosis factor NETs: Neutrophil extracellular traps AECOPD: Acute exacerbation of chronic obstructive pulmonary disease CRP: C-reactive protein sTNFR1: ...