The large superfamily of labdane-related diterpenoids is defined by the cyclization of linear geranylgeranyl pyrophosphate (GGPP), catalyzed by copalyl diphosphate synthases (CPSs) to form the basic decalin core, the copalyl diphosphates (CPPs). Three stereochemically distinct CPPs have been found in...
(CDP). Theenzymesthat catalyze these reactions are referred to as the A and B activities, respectively, ofent-kaurene synthase. However, a more logical nomenclature was proposed by MacMillan.280Thus, the conversion of GGDP to CDP is catalyzed by copalyl diphosphate synthase (CPS) and CDP to...
翻译 ent-copalyl diphosphate 翻译 烯丙基焦磷酸 以上结果来自机器翻译。 释义
SmCPSent catalyzes the cyclization of GGPP to ent-copalyl diphosphate (ent-CPP), which is converted to ent-kaurene by SmKS. Then, SmKO catalyzes the three-step oxidation of ent-kaurene to ent-kaurenoic acid. Our results show that the fused enzyme SmKS-SmCPSent increases ent-kaurene ...
SmCPSentcatalyzes the cyclization of GGPP toent-copalyl diphosphate (ent-CPP), which is converted toent-kaurene by SmKS. Then, SmKO catalyzes the three-step oxidation ofent-kaurene toent-kaurenoic acid. Our results show that the fused enzyme SmKS-SmCPSentincreasesent-kaurene production by ...
Summary Isoprenyl diphosphate synthases (IDSs) catalyze some of the most basic steps in terpene biosynthesis by producing the prenyl diphosphate precursors of each of the various terpenoid classes. Most plants investigated have distinct enzymes that produce the short-chain all- trans ( E ) prenyl ...
Köksal M, Hu H, Coates RM, Peters RJ, Christianson DW: Structure and mechanism of the diterpene cyclase ent-copalyl diphosphate synthase. Nat Chem Biol 2011, 7: 431–433.Koksal M, Hu H, Coates RM, Peters RJ, Christianson DW: Structure and mechanism of the diterpene cyclase ent-copalyl...
Bifunctional abietadiene synthase: Free diffusive transfer of the (+)-copalyl diphosphate intermediate between two distinct active sites. J. Am. Chem. Soc. 2001; 123:8974-8978. [PubMed: 11552804]Peters RJ, Ravn MM, Coates RM, Croteau RB (2001) Bifunctional abietadiene synthase: free ...
EC number 5.5.1.14 Systematic name 9伪-copalyl-diphosphate lyase (decyclizing) Recommended name syn-copalyl-diphosphate synthase Synonyms OsCPSsyn [2] OsCyc1 [1] syn-CDP synthase [1] syn-copalyl diphosphate lyase (decyclizing) syn-copalyl diphosphate synthase [1,2] CAS registry number 173585...
Ravn MM, Coates RM, Flory JE, Peters RJ, Croteau R (2000) Stereochemistry of the cyclization-rearrangement of (+)-copalyl diphosphate to (-)-abietadiene catalyzed by recombinant abietadiene synthase from Abies grandis. Org Lett 2: 573-576...