CO during the night (Figure 1a)[12,13]. Mutants ofcop1flower early under SDs and the phenotypes are largely suppressed in thecomutant background. COP1, through its WD40 repeats domain, interacts physically with CO (discussed below), ubiquitinates COin vitroand promotes CO degradationin vivo....
The specific expression of Cpt1a in the early stage of tumors, rather than Arg1, might support the theory that BMNs at the early stage of tumors possess the characteristics of spontaneous migration. Consistent with these observations, co-culture of LLC or A549 cells remarkably enhanced the ...
Whatever the mechanism, it is important to emphasize that these two forms were extracted in different conditions and that only the faster-migrating form was downregulated by the ectopic expression of COP1, suggesting that they locate in different compartments within the cell and that one of the ...
(Fig. 1b;Supplementary Figs 2b,d and 3e) are mostly sub-distant and comparatively close in one form. Macromorphological features of these fossils resemble extant mushrooms. In particular, two of four forms (Taxon A and B;Fig. 1a,c;Supplementary Fig. 2a,c) are similar to the extant ...
we identified and isolated 13 additional extragenic dominant suppressors ofcop1-6(Fig.1a). When grown in the dark, the hypocotyl lengths of all the dominant suppressor mutants were drastically longer than those ofcop1-6(Fig.1a). However, the suppression degrees showed some differences among these...
The COP9/signalosome (CSN), a multiprotein complex consisting of eight subunits, is implicated in a wide variety of regulatory processes including cell cycle control, signal transduction, transcriptional activation, and plant photomorphogenesis. Some of
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Our data show that SAP130 is a general cullin binding protein that normally associates with neddylated form of endogenous cullins in vivo. The preference of SAP130 for neddylated cullins is dependent on CAND1, a protein that specifically binds un-neddylated cullins. SAP130 predominantly binds ...
1a, CoMo precursor/NF-10 exhibits two intense diffraction peaks at 34.1 and 59.1°, which is ascribed to (111) Conclusion To summarize, with the involving of MoO linkage, the electrocatalytic activity of CoP for water splitting was significantly improved. The optimal sample, CoP/MOL/NF-10 ...
During maturation, eukaryotic precursor RNAs undergo processing events including intron splicing, 3′-end cleavage, and polyadenylation. Here we describe nanopore analysis of co-transcriptional processing (nano-COP), a method for probing the timing and p