Cooling the body appears to prevent brain damage after cardiac arrest
Cardiac arrest is a major cause of unexpected death in developed countries, with survival rates ranging from less than 5 % to 35 % [1,2]. In patients who are initially resuscitated, anoxic neurological injury is an important cause of morbidity and mortality [3]. For successful resuscitation, ...
Meurer and Silbergleit are principal investigators of a new clinical trial that will explore whether whole-body cooling improves the survival and recovery of comatose patients after a cardiac arrest, and if increasing durations of cooling are associated with better outcomes and recovery in these patien...
Cooling the body down to about 89.6 degrees after cardiac arrest protects it againstneurological damageinitiated by the lack of blood flow and oxygenation, several studies of out-of-hospital cardiac arrest patients have shown. It has also been shown to improve survival—a welcome development, since...
The Body After Death You may have heard of rigor mortis, which is the stiffening of the body after death. However, the body goes through other changes after dying as well. One of these is that it gradually loses the heat the body always retained in life, since there are no longer funct...
Background— Recent clinical studies have demonstrated that hypothermia to 32° to 34°C provides significant clinical benefit when induced after resuscitation from cardiac arrest. However, cooling during the postresuscitation period was slow, requiring 4 to 8 hours to achieve target temperatures after ...
Use of prehospital-induced hypothermia after out-of-hospital cardiac arrest: a survey of the National Association of Emergency Medical Services Physicians. Objective. Postresuscitation care of comatose survivors of cardiac arrest using induced hypothermia (IH) is recommended by the American Heart Associati...
Influence of Cooling duration on Efficacy in Cardiac Arrest Patients (ICECAP): study protocol for a multicenter, randomized, adaptive allocation clinical trial to identify the optimal duration of induced hypothermia for neuroprotection in comatose, adult survivors of after out-of-hospital cardiac arrest...
Case presentation: cooling (case with comatose survival of cardiac arrest)Jack Wei Chieh Tan
Cardiac Arrest and Therapeutic Hypothermia During cardiac arrest, the body's blood supply is interrupted and cells are deprived of oxygen. This stresses the body, causing the release of toxic compounds that can overwhelm the organs and result in long-term brain injury. Therapeutic hypothermia slows...