104 A total of 3,577 patients were randomized to ramipril (10 mg/day) or placebo, and vitamin E or placebo (2×2 factorial design). Treatment with ramipril reduced the risk of overt nephropathy by 24% (95% confidence interval 3 to 40, p = 0.027), and that of the combined primary ...
CGS 13080, a selective thromboxane synthetase inhibitor, was given intravenously (0.6 mg/kg over 6 hours) to eight hypertensive (diastolic 95-115 mm Hg) euvolemic caucasian females on their customary salt intake (24 hour urine Na: 142.9 +/- 14.8 meq). No change occurred in blood pressure ...
Interventions Participants were randomly assigned to receive chlorthalidone, 12.5 to 25 mg/d (n = 15 255); amlodipine, 2.5 to 10 mg/d (n = 9048); or lisinopril, 10 to 40 mg/d (n = 9054) for planned follow-up of approximately 4 to 8 years. Main Outcome Measures The primary outcome...
27. The process of any of claims 1 to 26, wherein the refined oil includes copper below about 0.05 mg/kg, phosphorous below about 0.2 mg/kg and is essentially free of pesticides. 28. The process of any of claims 1 to 27, wherein the omega3 fatty acid concentration is substantially ...
mg) are combined and dissolved in 0.005 M ammonium acetate (5 ml) and applied to the top of the column. Elution is carried out with 0.005 M ammonium acetate and is monitored by UV absorption. All the tubes showing a significant UV absorption at 280 mμ are pooled, concentrated to ...
After hydrochlorothiazide (100 mg daily) was added to the captopril, the supine mean blood pressure of 122 ± 5 mm Hg was significantly lower than during captopril alone (134 ± 4 mm Hg, P<0.01). Heart rate increased from 79 ± 3 to 90 ± 5 beats/min (P<0.05). In 13 of the 16...
Amiloride, at doses of 10-40 mg/day, increased mean plasma potassium levels in both primary hyperaldosteronism (3.2-4.5 mEq/L) and, to a lesser extent, in Bartter''s syndrome (2.5-3.6 mEq/L) The blood pressure fell slightly but significantly in primary hyperaldosteronism (171/112 vs 150/...
Two NIDD patients discontinued the medication, one because of symptomatic postural hypotension and the other, who had a plasma creatinine level of 1.8 mg/dl, because of hyper-kalaemia (K = 6.1 mEq/L ). In the responders, enalapril did not alter glucose tolerance, plasma or urinary excretion...
They were then instructed to reduce their sodium intake to about 80 mmol(mEq)/day. After two weeks of moderate sodium restriction they were entered into a double blind randomised crossover study comparing the effect of 10 Slow Sodium tablets (100 mmol sodium chloride) with matching placebo ...
CGS 13080, a selective thromboxane synthetase inhibitor, was given intravenously (0.6 mg/kg over 6 hours) to eight hypertensive (diastolic 95–115 mm Hg) euvolemic caucasian females on their customary salt intake (24 hour urine Na: 142.9 ± 14.8 meq). No change occurred in blood pressure or...