miRTarbase v7 collects 502652 records of human miRNA-mRNA inter- action pairs, where miRNA names and the gene symbol and Entrez ID information of the target mRNAs are pro- vided [25]. But it doesn't involve the miRNA accession. As mentioned above, a miRNA accession is the identi- fier ...
For concentrations that fell below this threshold, we used a value equal to the LOD divided by the square root of 2 in our analyses. Additional information on this method can be found in Additional file 1. Analysis of leukocyte global DNA methylation levels In this study, we measured 5mdC/...
Exon 13 encodes for the 67 amino acids of the NH2-terminal region of the testicular ACE, whereas downstream exons encode a sequence common to both isozymes. The gene duplication suggested by the internal homology of the endothelial ACE mRNA is now confirmed by the presence of two homologous ...
2C). The expression of ACE2 decreased in BTT 3033 treated HK-2 cells compared to DMSO treated cells (Fig. 2D). This data suggests that the integrin β1 activation determines the ACE2 expression in renal epithelial cells. Protein and mRNA levels of ACE2 were investigated using qRT-PCR and...
Patients were diagnosed as having essential hypertension according to the criteria of the World Health Organization, i.e., primary hypertension with systolic blood pressure (SBP) of more than 140 mmHg and/or diastolic blood pres- sure (DBP) of more than 90 mmHg. Genomic DNA was extracted from...
Moreover, ACE2 mRNA, protein, and enzymatic activity are developmentally regulated in a tissue-specific manner. In addition, Ang II, exerts a negative feedback on ACE2 in the adcetvinelgotphinrogukgihdnAeTy1.R, Copyright © 2012 International Pediatric Research Foundation, Inc. Volume ...
1992. Left ventricular hypertrophy due to volume overload versus pressure overload. Am J Physiol (Heart Circ Physiol 32):H1137–H1144. Bishop SP, Meisen LR. 1976. Myocardial necrosis, fibrosis, and DNA synthesis in experimental cardiac hypertrophy induced by sudden pressure overload. Circ Res ...
Dna Sequence the Journal of Sequencing & MappingKomatsu T, Suzuki Y, Imai J, Sugano S, Hida M, Tanigami A, Muroi S, Yamada Y, Hanaoka K (2002) Molecular cloning, mRNA expression and chromosomal localization of mouse angiotensin- converting enzyme-related carboxypeptidase (mACE2). DNA Seq ...
(Figure1). This granularity ranges from very fine, at the level of DNA microarrays (tens of bases in length, containing probe level information relevant to only a short region of the corresponding mRNA molecule) through coarser granularity with sequence reads (few hundreds), transcripts (...
Komatsu, T. et al. Molecular cloning, mRNA expression and chromosomal localization of mouse angiotensin-converting enzyme-related carboxypeptidase (mACE2).DNA Seq.13, 217–220 (2002) ArticleCASPubMedGoogle Scholar Harmer, D., Gilbert, M., Borman, R. & Clark, K. L. Quantitative mRNA expressio...