(e) An experimental scheme to evaluate the regulatory activity of infused antibody. (f) Arthritis score of each group of mice is presented. Each symbol represents the result from an individual mouse. Mean values were presented as bars. The data are representative of three independent experiments....
the decrease of BFU-E formation. Importantly, GW4869 efficiently prevented the effect of TNFα by restoring the score of BFU-E/CFU-E to 78%, whereas desipramine reduced BFU-E/CFU-E formation concurrently to an enhancement of myeloid subpopulations (Fig.2dand Supplementary TableS2). TNFα an...
34,35 The significance of the ascertained biological processes was calculated using the “Ease score,” a modified 1-tailed Fisher Exact Probability Value, which was further corrected for false discovery rate using the Benjamini correction. Unique dataset determination Datasets of genes uniquely ...
(a) An experimental scheme to evaluate the regulatory activity of infused antibody is presented. (b,c) Frequency (b) and score (c) of arthritis are plotted. Each symbol represents the result from an individual mouse. Data are representative of three independent experiments; these were analysed ...
Intra-articularly injected GDF5-transfected autologous BM-MSCs demonstrated a similar effect according to the high histological score assessment [87]. In contrast, another publication reported that GDF5 induced the tenogenic differentiation of BM-MSCs and a significant down-regulation of non-tenogenic ...