The MDRD equation, used to calculate "eGFR", was originally developed using a conventional serum creatinine assay and later was republished using IDMS-based values. The update to MDRD, called the CKD-EPI equatio
Secondary safety endpoints included: the mean change from baseline in estimated creatinine clearance (Cockcroft-Gault) and eGFR; incidence of any opportunistic infection or malignancy within 12 months; the proportion of patients with hemoglobin A1c (HbA1c) ≥6.5%; change from baseline in HbA1c; chan...