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reproductive organs. In addition, a homologue ofdmd-1exhibits male-specific expression inSchistosoma mansoni, a derived, dioecious flatworm. These results demonstrate conservation of the role of DM domain genes in sexual development in lophotrochozoans and suggest one means by which modulation of ...
This homeostatic feeding is tightly controlled by the activity of brain networks and circulating hormones [2–4]. On the other hand, hedonic feeding is driven by the pleasure of consuming palatable food without a metabolic need, which is a major factor contributing to overeating and obesity [5]...
Collectively, these results reveal a physiological role of aa-Rab1A-mTORC1 signaling in the control of whole-body glucose homeostasis in mammals. Intriguingly, Rab1A expression is reduced in β-cells of type 2 diabetes (T2D) patients, which is correlated with loss of insulin expression, ...
Furthermore, the precise timing of each molt (L1/L2 and L2/L3), and the onset of metamorphosis, are finely regulated in a stereotyped manner by pulses of ecdysteroid hormones (Riddiford, 1993). If the ecdysteroids synthesis pathway is affected, it induces a gradient of phenotypes ranging ...
Associations between endocrine variables and age, gender, BMI, change of plasma glucose levels, and change of appetite level were assessed by nonparametric Kendall's τ correlation. Means and standard deviations are reported. The level of significance was set to p=0.05. RESULTS Effects on Appetite...
Auxin, one of the major plant hormones, is essential to regulate diverse processes of plant development by coordination of cell expansion and cell division, such as embryogenesis, tropic response, shoot branching, vascular development, apical dominance, flowering and fruit ripening [11,12]. The effe...
ARL13B is a small regulatory GTPase that controls ciliary membrane composition in both motile cilia and non-motile primary cilia. In this study, we investigated the role of ARL13B in the efferent ductules, tubules of the male reproductive tract essential to male fertility in which primary and mo...
In vertebrates, this regulatory task is assigned to the HPA (hypothalamic-pituitary-adrenal) axis, including the hormones epinephrine and norepinephrine, which mediate organ reactions to a great variety of stressors. The multifaceted fight-or-flight response is a prime example of a stress reaction ...
The cellular responses to hormones and other homeostatic stimuli are characterized by timed and coordinated transcriptional regulation of specific gene subsets. In the case of mitogens, for example, the stimulus induces ordered gene activation and repression events occurring at specific times after exposur...