In this regard, note that certain correlations appear to exist between the nuclear sizes and RNA transcription levels2,46; and that the activity of DNA polymerase was found to be sensitive for macromolecular crowding47,48,49. Context-dependent polarization is important for the functional plasticity...
TCF/Lef1 activity controls establishment of diverse stem and progenitor cell compartments in mouse epidermisdoi:10.1038/emboj.2011.199epidermisLef1sebaceous glandskinstem cellMammalian epidermis consists of the interfollicular epidermis, hair follicles (HFs) and associated sebaceous glands (SGs). It is ...
Earlier studies demonstrated that GAPDH is a nucleic acid binding protein that prevents rapid shortening of telomeric DNA, is involved in transport of tRNA and mRNA, regulates expression of genes via specific binding to the 5′UTR and 3′UTR of mRNA and possesses uracil DNA glycosylase activity ...
47 As a consequence of EGFR activation and the delay in anagen entry in first telogen stage upon loss of Dsg3 transadhesion (Figures 4 and S1C), we expected reduced Wnt activity upon AK23 treatment. However, canonical Wnt also regulates self-renewal of epidermal keratinocytes,48 suggesting a ...
Comparison of nuclei density in ring glands of given genotypes was performed with a Two-sample Kolmogorov-Smirnov test, p < 0.05 when data of two sets are significantly different. 3. Results 3.1. Drosophila larval development is temporally affected in the absence of AurA kinase activity In ...
Various emotional states give rise to certain patterns of electrical activity in the facial muscles and in the brain. Is the statement true or false? Male and female brains look identical in brain scans during problem solving. True or false?
Production facilities can be found in Germany, the United States, India, Brazil and China. With a global distribution network in more than 80 countries, Internormens world-wide business activity is increasingly developed. Physicists, chemists, engineers and technicians are on a quest for the perfe...
Neuroblastoma is a cancer of immature nerve cells and occurs mainly in children younger than six years of age. The tumors are typically found on top of adrenal glands but can also develop in the abdomen, chest, neck, pelvis, and bone. Approximately 500 to 1,000 cases are diagnosed annually...
The activity of the channel is critical, since its inhibition using small molecules reduces extracellular matrix invasion48. In comparison, and while SCN5A was expressed at the mRNA level, no transient sodium current could be recorded in non-tumoural immortalized MCF-10A mammary cells, or even ...
Within the male mammalian reproductive system, the efferent ductules are small tubules responsible for conveying sperm from the testis to the head of the epididymis1,2. During this process, the epithelium engages in a dynamic activity of fluid reabsorption, leading to an approximately 28-fold increa...