Laura and Isaac Perlmutter Cancer Center, NYU School of Medicine, New York, NY, USA Maria Guillamot, Igor Dolgalev, Nikos Kourtis, Yuling Dai, Kate Corrigan, Luna Zea-Redondo, Anastasia N. Tikhonova, Marina Malumbres, Yixiao Gong, Aristotelis Tsirigos, Christopher Park & Iannis Aifantis De...
According to the ladder model, the cGAS2–DNA2 assembly is ineffective and unstable, but it triggers the binding of subsequent cGAS to form the cGAS2n–DNA2 (n ≥ 2) ladder. As a result, the longer DNA should more notably activate cGAS. Interestingly, even if the short-length DNA...
you don’t need to specify the type of the platform view (e.g. usePlatformBehavior<T>); you probably want to apply yourBehaviorin more than one control, in that case the platformView will be anPlatformBehavior<View>onAndroidand anPlatform...
Non-host structures trigger the alternative pathway which may lead to their elimination by phagocytosis or cell...doi:10.1016/j.imbio.2012.08.190Adriana G.P. MartínezViviana P. FerreiraTatiana R. FragaSilvio de Arruda VasconcellosMohamed R. DahaAngela S. BarbosaLourdes IsaacElsevier GmbHImmunobiology...
Now, using the FMO control and resulting FMO bound, the experimenter is able to set the proper gate and ensure that the spread of the data (blue double arrow on the far right), is not impacting his or her gating. In the more complex example below, the plots show a population of circu...
According to the ladder model, the cGAS2–DNA2 assembly is ineffective and unstable, but it triggers the binding of subsequent cGAS to form the cGAS2n–DNA2 (n ≥ 2) ladder. As a result, the longer DNA should more notably activate cGAS. Interestingly, even if the short-length DNA (<...
of different wheat species and varieties; E. Paux and H. Rimbert (INRA GDEC) for providingStb6expression data at different developmental stages; A. Doherty, A. Huttly, and C. Sparks (Rothamsted Research, Harpenden, UK) for vectors and wheat transformation; P. Isaac (iDNA Genetics Ltd., ...
NMDA receptor-dependent long-term depression (NMDAR-LTD) is a long-lasting form of synaptic plasticity. Its expression is mediated by the removal of AMPA receptors from postsynaptic membranes. Under basal conditions, endocytosed AMPA receptors are rapidl
SLE non-coding genetic risk variant determines the epigenetic dysfunction of an immune cell specific enhancer that controls disease-critical microRNA expressionGuojun Hou, Isaac T. W. Harley, Xiaoming Lu, Tian Zhou, Ning Xu, Chao Yao, Yuting Qin, Ye Ouyang, Jianyang Ma, Xinyi ...
The bidirectional communication between the immune and nervous system is important in regulating immune responses. Here we show that the adrenergic nerves of sympathetic nervous system orchestrate inflammation resolution and regenerative programs by modu