A changing understanding of the disease dental caries has initiated a paradigm shift in the management of caries and carious lesions. Instead of merely removing the symptoms of the disease (i.e., the carious lesion), the aim of any therapy is to manage the disease. Noninvasive (biofilm cont...
resulting from an imbalance in the demineralization (DEM) and remineralization (REM) process [1]. Commensal microorganisms are able to metabolize carbohydrates and produce acids that can initiate tooth structure DEM. In individuals on a low-sugar diet, a physiological mechanism such as salivation is...
osteoblast/osteoclast numbers. Specifically, the model indicated that osteoclast activity must vary greatly (> 17-fold) to return the bone volume to baseline after injury and suggest that osteoblast/osteoclast number alone is insufficient to predict bone the trajectory of bone repair. Importantly, t...
The Syk tyrosine kinase localizes to the centrosomes and negatively affects mitotic progression. Cancer Res. 65, 10872–10880 (2005). Article CAS PubMed Google Scholar Fourest-Lieuvin, A. et al. Microtubule regulation in mitosis: tubulin phosphorylation by the cyclin-dependent kinase Cdk1. ...
Differential expression of miRNAs in the visceral adipose tissue of patients with non-alcoholic fatty liver disease. Aliment Pharmacol Ther 2010; 32: 487鈥 497SummaryBackground Progression of non-alcoholic fatty liver disease (NAFLD) can be facilitated by soluble molecules... M Estep,D Armistead,...
Human induced pluripotent stem cell-derived neural progenitor cells (hNPCs) are a promising cell source for stem cell transplantation to treat neurological diseases such as stroke and peripheral nerve injuries. However, there have been limited studies investigating how the dimensionality of the physical...
Inadequate LH secretion and lack of pre-ovulatory surge inhibit the progression of the follicular phase of a menstrual cycle and result in anovulation and amenorrhea. The main consequences of lactational amenorrhea are connected with fertility issues and increased bone turnover. Provided the fulfillment...
Although β-catenin is involved in many phases of cancer progression and higher levels worsen prognosis [220,226], little is known on whether different amounts of Wnt protein accumulation relate to specific phases of carcinogenesis. 5. Conclusions and Future Directions The pleiotropic roles of the ...