ContextAlcohol dependence treatment may include medications, behavioral therapies, or both. It is unknown how combining these treatments may impact their
VUE is two parallel, pragmatic, UK multicentre, RCTs (Uterine Trial and Vault Trial). Eligible for inclusion are women with vault or uterine prolapse: requiring a surgical procedure, suitable for randomisation and willing to be randomised. Randomisation will be computer-allocated separately for each...
Medications Mortality To enable this, participants will be asked to consent to the research team sharing identifiable information with these data providers. Routine data will be sent to CTRU via a secure file transfer system. Sample size One thousand three hundred thirty-seven participants (371 ...
Music therapy is a complex intervention provided by music therapists that uses a range of expressive and receptive musical activities, verbal reflection and the relationships developed through this to improve health [30]. Within the United Kingdom (UK), music therapists are regulated by the Health ...
20 However, a full cost effectiveness analysis is under preparation, accounting for the impact on use of health services and medications. The weight loss observed in the 10TT arm may reflect a change in those behaviours targeted, and the maintenance of this weight loss could reflect the fact ...
Randomised participants who take prohibited medications will cease participation. Such participants will remain in the trial and will be included in the primary, intention-to-treat analysis, but excluded from the per-protocol analysis. Doxycycline interacts with barbiturates (e.g. phenobarbitone), ...
Concomitant medications/treatments These will be administered to all patients in accordance with the existing LWH PN guidelines and LWH NICU drug formulary. The study will not affect the use of concomitant medications/treatments. Methods: Assessments and Procedures ...
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental condition characterized by developmentally-inappropriate, persistent, pervasive and impairing inattention and/or hyperactivity/impulsivity symptoms [1]. ADHD medications, particularly psychostimulants, provide both clinically significant symptomati...
Patients may hold beliefs about the causes of respiratory tract infections [22–24], the meaning of symptoms [25, 26], and the effectiveness of medications [22, 23, 25, 27], that are at odds with biomedicine. Providing parents with written information about respiratory tract infections in ...
Only very few participants in each group used other NHS interventions or weight-loss medications, and only a small proportion of participants who were assigned to the brief intervention group went on to use a commercial weight-loss programme. A strength of this trial is the 2-year follow-up ...