A program and computer interface have been developed to enable computer controlled drug administrations that simulate patterns of self-administration of drugs.doi:10.1016/0165-6147(83)90485-6A. P. LecceseW. H. LynessJ. H. PirchElsevier LtdTrends in Pharmacological Sciences...
A procedure is described for the infusion or repeated injection of drugs into the unanesthetized unrestrained pigeon by means of a chronic indwelling i.v. ... ID Administration - 《European Journal of Pharmacology》 被引量: 12发表: 1973年 ...
Potential limitations of this trial include the following: the complicated blinding procedure might also present a potential weakness of the trial. In order to preserve blinding of all clinicians and research staff involved, it is necessary to involve different members of staff at nearly every point ...
(iii) a radiographic grade of 1 or > 2 according to the Kellgren-Lawrence scale; (iv) a history of knee joint surgery; (v) consumption of nonsteroidal anti-inflammatory drugs within the preceding three months for knee pain; and (vi) intra-articular administration of hyaluronic acid and...
(s) require further elucidation, inflammation, damage to the intestinal membrane, and translocation of bacteria have all been suggested7. Drugs with antifibrotic or anti-inflammatory treatments for various stages of NAFLD in human trials is pending8. Currently, increased physical activity and dietary ...
GLP-1 analogues are widely studied and used as food-intake regulating hormones. It is likely that food-related and drug-induced reward processing share common mechanisms. Based on recent animal data, showing that GLP-1 controls reward induced by nicotine and other addictive drugs, similar effects...
The co-primary endpoints of this study are vasomotion (change in mean lumen diameter before and after nitrate administration at 3 years) and difference between minimum lumen diameter (after nitrate administration) after the index procedure and at 3 years. Secondary endpoints were procedural performance...
Administration of other medications for paralytic ileus, n (%)‡ 2 (1.9) 1 (1.0) .999 ∗ Median (97.5% confidence interval). † Mean ± standard deviation. ‡ Administration of other drugs to improve bowel motility. With regard to the incidence of paralytic ileus, a comparison between...
Flu-like symptoms are the main side effects of intravenous administration. Transdermal drug delivery results in local toxicity caused by the release of too much drug over a short period of time11. Overall, these drugs are very effective, but better delivery methods are required. One of the ...
one week after the probiotic intervention indicated their prolonged effect. Our results suggested that a long-term intake of these probiotics is needed to achieve a significant effect on constipation symptoms and their effectiveness may be reduced by the concomitant use of laxative drugs. This is in...