Although ICH GCP recommendations are aimed primarily at drug trials, to acquire evidence for licensing, they have been considered relevant also for trials of medical devices. They were designed to safeguard patients while promoting the utility and transparency of RCTs, but now the bureaucratic burden...
WO2003080026A1 Mar 22, 2002 Oct 2, 2003 Ranbaxy Laboratories Limited Controlled release drug delivery system of pravastatinWO2003080026A1 * 2002年3月22日 2003年10月2日 Ranbaxy Laboratories Limited Controlled release drug delivery system of pravastatin...
There is evidence that the patient would be unable to adhere to trial procedures or complete questionnaires, such as cognitive impairment or intravenous drug abuse Trial Interventions All of the hospitals involved in this trial currently use both of the methods of fixation and all of the surgeons ...
(drug–placebo RDs) of individual antidepressants and classes, and to consider factors associated with year-of-reporting by bivariate and multivariate regression modeling. Observed drug–placebo differences were moderate and generally similar among specific drugs, but larger among older antidepressants, ...
Considering the concurrent use of medications, variations in drug metabolism, a higher risk of adverse effects, and the presence of comorbid medical conditions, this population may exhibit greater sensitivity to pharmacological interventions compared to younger individuals93. Based on our review, non...
Employment is a vital source for experiencing well-being and lowering the risk of long-term social marginalisation and poverty. For persons with alcohol and drug addiction, it may also improve sobriety. However, the unemployment situation for this group
Controlled or sustained release dosage forms provide a therapeutic dose of the drug soon after administration, and then gradually release the drug over an extended period of time. The primary method of accomplishing this controlled release has been through incorporating the drugs within polymers or to...
E-cigarettes and other THR products are imported legally as a consumer good and are taxable. Currently, the use of THR, mainly e-cigarettes, is unregulated and limited to the upper and middle classes due to their higher prices and limited access to the economically deprived areas of Pakistan....
Antibody-drug conjugates (ADCs), which typically comprise a full IgG molecule linked to cytotoxic payloads, are one of the fastest-growing classes of biotherapeutics, and have the potential to revolutionise PaCa therapy.2,3,4 These agents exploit the targeting ability of antibodies to deliver a ...
Engler, A. C. et al. Emerging trends in macromolecular antimicrobials to fight multi-drug-resistant infections.Nano Today7, 201–222 (2012). ArticleCASGoogle Scholar Winson, M. K. et al. Construction and analysis of luxCDABE-based plasmid sensors for investigatingN-acyl homoserine lactone-media...