An MnSOD Assay Kit with WST-8 was used to evaluate mitochondrial ROS activity in HMCs, according to the manufacturer's instructions. To measure cellular GSH and MDA levels, HMCs were collected and assayed using GSH and MDA kits, according to the manufacturer's respective instructions....
This 234 nt circRNA, hsa_circ_0022614, identified in the human reference genome (GRCh37/hg19), originates from the exon 2 and exon 3 regions of the microtubule affinity regulating kinase 2 (MARK2) gene (chr11:63662630–63663105), and is thus referred to as circMARK2 (Fig. S1B). We ...
This study aims to identify miRNA–mRNA regulatory pathways associated with HBV-related HCC. Therefore, after conducting KEGG pathway enrichment analysis, several HBV-related HCC pathways were selected for further analysis. For upregulated potential DE-miRNAs, three enriched pathways including hsa05161, ...
Finally, three competing endogenous RNA regulatory networks were built using lncRNAs that significantly correlated with immune cell types, miRNAs that responded to EBV infection, and potentially targeted the mRNA of the miRNAs. Among them, MRPL42-AS-5 might act as an hsa-miR-296-5p "sponge" ...
- Add an HCC definition and Doxygen comments for the function in include/hcc_detail/hip_runtime_api.h - Source implementation typically go in src/hcc_detail/hip_hcc.cpp. The implementation may involve calls to HCC runtime or HSA runtime, or interact with other pieces of the HIP runtime ...
The functional protein has 3 well-differentiated domains connected by linker regions that provide flexibility to the general structure. The N-terminal domain, ranging from Glu27 to Glu67, includes an Excalibur domain (from extracellular calcium-binding region, pfam05901). Although its function is ...
an RNA helicase (elF4A) and elF4E,the cap-binding protein[154]. Initiation factor elF 4E is the rate limiting factor and its binding to elF4G is regulated by elF4E–binding protein (4E-BP) causing suppression of translation [155]. Phosphorylation of 4E-BP in response to mitogenic stimuli...
Nab-paclitaxel, a formulation of paclitaxel bound to human serum albumin (HSA) NPs, was the first protein NP successfully used in the clinic [16]. Albumin was used as an alternative for CrEL in the formulation of paclitaxel because of its low toxicity and preferential uptake by cancer cells ...
This study suggests that not only fungistatic activity (MIC), but also fungicidal activity in the presence of keratin, is an important factor contributing to the in vivo efficacy of topical antifungal drugs against onychomycosis. Keywords: onychomycosis; topical antifungal; drug effect; keratin; ...
They have role models, so if it is a woman saying it, it is great to look up to her and who she is. It really depends on who is standing there" (maker, Denmark). Interviewing maker managers, however, also had an impact on their reflection of male dominated cultures: "The visibility...