The relaxation mechanisms (inner sphere, second sphere, and outer sphere) governing the effect of MRI contrast agents are described. Two kinds of agents, i.e., paramagnetic Gd complexes and superparamagnetic iron oxide nanoparticles, are presented and their efficiency (relaxivity) is developed. Some...
Radiology Contrast AgentsUltrasound Imaging Contrast Agents Contrastagents are chemical substances introduced to the anatomical or functional region being imaged, to increase the differences between different tissues or between normal and abnormal tissue, by altering the relaxation times.MRIcontrastagents are ...
Lauffer RB (1991) Targeted relaxation enhancement agents for MRI. Magn Reson Med 22:339–342, 343–346 PubMedGoogle Scholar Lauffer RB, Parmelee DJ, Dunham SU, Ouellet HS, Dolan RP, Witte S, McMurry TJ, Walovitch RC (1998) MS-325: albumin-targeted contrast agent for MR angiography. Radi...
2.Basic Principles of MRI Contrast Agents ‘Contrast’ refers to the signal differences between adjacent regions,which could be‘tissue and tissue’, ‘tissue and vessel’,and ‘tissue and bone’. Contrast agents for X-ray and CT show contrasting effects according to the electron-density differenc...
MRI contrastcomputed tomographynephrogenic systemic fibrosisMagnetic Resonance Imaging (MRI) as a diagnostic tool is becoming increasingly available in Nepal and more and more patients undergo MRI examination today. It was also traditionally believed that MRI contrast agents are safer than Computed ...
Thanks to the ever-advancing technologies, cardiac magnetic resonance imaging (MRI) has become a major diagnostic tool in clinical cardiology for acquisition of morphological, functional and metabolic information. However, it is of no doubt that only when complemented with the use of contrast agents,...
Superparamagnetic iron oxide (SPIO) MR contrast agents are composed of nano-sized iron oxide crystals coated with dextran or carboxydextran. Two SPIO agent... YXJ Wang - 《Quantitative Imaging in Medicine & Surgery》 被引量: 560发表: 2011年 Contrast agents for MRI Molecular imaging is a rapidl...
Smart contrast agents for mri imagingThe present invention pertains to a contrast agent for MRI imaging comprising: (a) one cyclodextrin, whose truncated-cone-shaped structure defines a central axis, a first and a second openings along said axis, (b) one paramagnetic element, located on said ...
Mn₃[Co(CN)₆]₂@SiO₂ core-shell nanocubes: novel bimodal contrast agents for MRI and optical imaging. Nanoprobes with dual modal imaging of magnetic resonance imaging (MRI) and two-photon fluorescence (TPF) can serve as promising platforms for clinical diag... Y Huang,L Hu,T Zhang...
Various inorganic nanoparticles have been used as magnetic resonance imaging (MRI) contrast agents due to their unique properties, such as large surface area and efficient contrasting effect. Since the first use of superparamagnetic iron oxide (SPIO) as a liver contrast agent, nanoparticulate MRI cont...