context-dependent effect of moodpredecisional processingneuroticismaction vs. state/volatility orientationThis study explored the influence of the context-dependent effect of mood as well as individual differences in neuroticism and action vs. state/volatility orientation on predecisional processing in a ...
Our results suggest that the timing of WGD during tumor growth and recurrence is a critical determinant of its effect on tumor growth. Although we did not detect spontaneous WGD in primary tumors, the induction of polyploidy in primary tumors accelerated their growth. This suggests that the absen...
Cellular senescence plays a critical role in tumorigenesis. Once thought of as a tissue culture artefact by some researchers, senescence is now a major field of study. Although there are common molecular mechanisms that enforce the growth arrest that cha
Provisioning with naturally-collected polyfloral pollen inverted the effect, reducing virus-induced mortality and suggesting a hormetic response. To test if the response was pesticide specific, we repeated our experiment with a pyrethroid (lambda-cyhalothrin) and a neonicotinoid (thiamethoxam), finding ...
Regarding the effect of PIN and TRZ, our results differed from those reported by other researchers, wherein PIN and TRZ did not affect the expression of locomotor sensitization to cocaine [67]. Show abstract Role of the treatment environment in the effects of aripiprazole on ethanol-induced ...
Evaluating the context-dependent effect of family history of stroke in a genome scan for hypertension. 来自 Semantic Scholar 喜欢 0 阅读量: 41 作者:AC Morrison,A Brown,SLR Kardia,ST Turner,E Boerwinkle 摘要: BACKGROUND AND PURPOSE: Hypertension is an important risk factor for stroke, and the...
Surprisingly, mesenchymal stromal cells modified with NRP1 supported expansion of HSPCs having enhanced functionality, suggesting that NRP1 exerts a context-dependent effect on hematopoiesis. Our data demonstrate that NRP1 is an important niche component and exerts context-dependent effects on the HSPCs....
In ER-negative breast cancer, however, the opposite effect of GCs was observed, and GR expression was associated with worse survival (Table1) and with poor outcome in response to taxane-based chemotherapy. Also, this study showed that high GR expression was associated with improved outcomes in ...
We found that this effect was present in glucose and was accentuated in galactose (initial missense heteroplasmy in highly heteroplasmic cells: 65.55 ± 1.10%; day 5: 56.87 ± 0.78% in glucose P < 0.001 versus 38.33 ± 4.4% in galactose P < 0.001 (Fig. 3c)...
(Fig.4d, e). The effect of AA was observed only when Fe3+were used. Thus, maintaining the redox state of iron Fe2+in the catalytic site to TET2 is most likely the mechanism of action of AA mediated increase in dioxygenase activity21. In such scenario, it is plausible to hypothesize ...