Contactin-associated protein1 (Caspr1) plays an important role in the formation and stability of myelinated axons. InCaspr1mutant mice, autophagy-related structures accumulate in neurons, causing axonal degeneration; however, the mechanism by which Caspr1 regulates autophagy remains unknown. To ...
contactin-associated protein-2 (CASPR-2; axon); contactin-2 (ensheathing glial cells); leucine-rich glioma inactivated 1 protein (LGI-1; synapse)) are detected in the sera of patients with peripheral nerve hyperexcitability (acquired neuromyotonia), Morvan's disease and limbic encephalitis [1...
1. A family of synapse-associated protein(SAPs) has recently emerged as a central player in the molecular organization of synapses. 突触相关蛋白家族成员的功能与神经突触膜上的谷氨酸酯受体和钾离子通道的定位和功能有关 ,参与神经递质的释放、神经的生长、发育及修复 。 更多例句>> 3) contactin 接触...
Anti-contactin 1 and contactin-associated protein 1 (Caspr1) antibodies were positive in the serum. She was subsequently started on rituximab 750mg/m2 every week for the 1st month and then once every 6 months. The patient has received 4 doses of rituximab treatment so far. At the last ...
CONTACTIN‐ASSOCIATED PROTEIN‐LIKE 4 (CNTNAP4)OSTEOGENESISLIGAND/RECEPTOR‐LIKE INTERACTIONNELL‐1/CNTNAP4 AXISNELL-1 is a novel secreted protein associated with premature fusion of cranial sutures in craniosynostosis that has been found to promote osteoblast cell differentiation and mineralization. Our ...
No effect of genetic deletion of contactin-associated protein (PR) on axonal orientation and synaptic plasticity. Journal of Neuroscience Research. 2007; 85 :2318–2331.Pillai AM , Garcia-Fresco GP , Sousa AD , Dupree JL , Philpot BD , Bhat MA ( 2007 ) No effect of genetic deletion of ...
1. A family ofsynapse-associated protein(SAPs) has recently emerged as a central player in the molecular organization of synapses. 突触相关蛋白家族成员的功能与神经突触膜上的谷氨酸酯受体和钾离子通道的定位和功能有关 ,参与神经递质的释放、神经的生长、发育及修复 。
Mutations in the Contactin-associated protein-like 2(CNTNAP2)gene are associated with autism spectrum disorder(ASD),and ectodomain shedding of the CNTNAP2 protein plays a role in its function.However,key enzymes involved in the C-terminal cleavage of CNTNAP2 remain largely unknown,and the ...
Contactin-Associated Protein-like 2 AntibodiesChristian G. Bien
HSE has mainly been reported in association with N-methyl-D-aspartate receptor (NMDAR) antibodies, but there have also been cases associated with contactin-associated protein-like 2 (CASPR2). This article aims to highlight the relevance of CASPR2 antibody generation in HSE. This is a case ...