Synonyms Genome-scale metabolic modeling Definition With the advent of high-throughput technology, there has been a growing need to develop computational frameworks that contribute to analyze these data for unveiling the biological principles underlying metabolic networks. Constraint-based modeling is a ...
COBRApy is a constraint-based modeling package that is designed to accommodate the biological complexity of the next generation of COBRA models and provides access to commonly used COBRA methods, such as flux balance analysis, flux variability analysis, and gene deletion analyses....
A system for constructive constraint-based modeling - Solano, Brunet - 1993 () Citation Context ...understood and remain invariant. This aspect makes the method unsuitable for constraint-based variant generation in which no explicit coordinate system should be assumed. Solano and Brunet propose in ...
Systems biology of bacterial nitrogen fixation: High-throughput technology and its integrative description with constraint-based modeling Osbaldo Resendis-Antonio, Magdalena Hernández, Emmanuel Salazar, Sandra Contreras, Gabriel Martínez Batallar, Yolanda Mora & Sergio Encarnación BMC Systems Biol...
It's fast:MIOM leverages the power of MIO solvers to solve complex optimization problems. You can control the quality and speed of the solutions for your problem and get better solutions that the approximations (LP) of the original problem available in other constraint-based modeling libraries. ...
Figure 1. Overview of the constraint-based modeling pipeline highlighting areas where machine learning has been applied using the oval shapes. It additionally depicts four categories of data sources and seven broad steps in the CBM modeling pipeline. ...
Dandekar T, Fieselmann A, Majeed S, Ahmed Z: Software applications toward quantitative metabolic flux analysis and modeling. Brief Bioinform. 2012, doi:10.1093/bib/bbs065 Google Scholar Lakshmanan M, Koh G, Chung BKS, Lee DY: Software applications for flux balance analysis. Brief Bioinform. ...
Systems biology of bacterial nitrogen fixation: High-throughput technology and its integrative description with constraint-based modeling Osbaldo Resendis-Antonio, Magdalena Hernández, Emmanuel Salazar, Sandra Contreras, Gabriel Martínez Batallar, Yolanda Mora & Sergio Encarnación BMC Systems Biol...
RESEARCH ARTICLE Host-Microbe Biology crossm Metabolic Analyses of Nitrogen Fixation in the Soybean Microsymbiont Sinorhizobium fredii Using Constraint-Based Modeling Carolina A. Contador,a Siu-Kit Lo,a Siu H. J. Chan,b Hon-Ming Lama aSchool of Life Sciences and Center for Soybean ...
SLIMEr: probing flexibility of lipid metabolism in yeast with an improved constraint-based modeling framework Your privacy, your choice We use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social ...