Gay and bisexual (GB) men with prostate cancer (PCa) have been described as an “invisible diversity” in PCa research due to their lack of visibility, and absence of identification of their needs. This study examined the meaning and consequences of erectile dysfunction (ED) and other sexual ...
We confirmed associations of longer genetically determined LTL with lower risk of coronary artery disease as well as with a higher risk of several organ-specific cancers, including prostate, melanoma, thyroid and kidney, and genitourinary tumors (uterine polyps and fibroids)3,11. We found new ...
In an attempt to have better targeting of the prostate during radiotherapy it is necessary to understand the mechanical interactions between bladder, rectu... L Keros,V Bernier,P Aletti,... - 《Medical Physics》 被引量: 31发表: 2006年 Cost analysis of erythropoietin versus blood transfusions...
This study systematically investigates the consequences of dose uniformity that results from the application or removal of an upper dose constraint ( ) in the inverse planning process for prostate treatments. sparing, target coverage, hotspots, and plan complexity were compared between prostate plans ...
Centromeres are the chromosomal domains required to ensure faithful transmission of the genome during cell division. They have a central role in preventing aneuploidy, by orchestrating the assembly of several components required for chromosome separation
(2002) Prostate cancer gene therapy and the role of radiation. Cancer Treat Rev 28: 49– 64.Garcia ML, Knaus HG. (1997) Complex subunit assembly of neuronal voltage-gated K+ channels. Basis for high-affinity toxin interactions and pharmacology. J Biol Chem 272: 27577– 27581.Kaufer D, ...
Copper-containing enzymes perform fundamental functions by activating dioxygen (O2) and therefore allowing chemical energy-transfer for aerobic metabolism. The copper-dependence of O2 transport, metabolism and production of signalling molecules are suppo
Thus, SSAT was conditionally overexpressed in LNCaP prostate carcinoma cells via a tetracycline-regulatable (Tet-off) system. Tetracycline removal resulted in a rapid approximately 10-fold increase in SSAT mRNA and an increase of approximately 20-fold in enzyme activity. SSAT products N(1)-...
Clonal hematopoiesis (CH), the clonal expansion of a blood stem cell and its progeny driven by somatic driver mutations, affects over a third of people, yet remains poorly understood. Here we analyze genetic data from 200,453 UK Biobank participants to m
Prolonged stress can reduce the activity of the innate type I interferon system, which is the earliest immune defence against viruses and is responsible for the removal of virus-infected cells. By suppressing natural killer (NK) cell activity, stress-increased cortisol production is associated with ...