A multivariate regression analysis showed that histidine concentrations were independently associated with hepatocyte growth factor, hemoglobin, and fetuin-A. In unadjusted analysis, a low histidine concentration was associated with all-cause mortality (log rank chi-square test = 8.9; P = 0.002). ...
We also found other evidence of ongoing TMA in the HUS-ascribed ESRD patients, including consistently higher lactate dehydrogenase and RDW levels, as well as lower platelet and hemoglobin levels, which may reflect a chronic ongoing low-grade disease process. Earlier studies have found high TMA ...
Why might an abnormally low RBC count be dangerous? What is the average lifespan of a red blood cells? List some effects of aging on blood vessels. What happens to hemoglobin-O_2 binding when tissues go from resting to active? Where are red blood cells broken down? What are the physiolo...
or strains. While multiple atomic resolution cryo-electron microscopy structures of α-synuclein fibrils are now deposited in Protein Data Bank, significant gaps in the biological consequences arising from each conformation have yet to be unraveled...
Despite the abundance of hydrogen and the ubiquity of acid-base reactions, the concentration (or, more properly, the chemical activity) of free hydrogen or hydronium ions is very low in most biological fluids.This is in part because these ions are constantly being consumed in a great variety ...
Hemoglobin-oxygen saturation was determined from nom- ograms for dogs (39). RA, Ao, and PA pressures, Ppl, QI,QK,and VT were recorded continuously. Gas pressures, pH, CO, and FRC were determined at the end of each control and test period. All dogs were observed for 30 min after the...
2) suggest an effect of LTL variation on lineage fate at the lympho-erythromyeloid progenitor level37. The contrasting associations of LTL with erythrocyte count versus erythrocyte size and hemoglobin content may reflect a primary effect on the maintenance of red blood cell mass38. However, for ...
Article: Trans-substitution of the proximal hydrogen bond in myoglobin: I. Structural consequences of hydrogen bond deletion
F. A kinetic model of protein synthesis. Application to hemoglobin synthesis and translational control. J. Biol. Chem. 254, 11927–11937 (1979). CAS PubMed Google Scholar Mathews, M. B., Sonenberg, N. & Hershey, J. W. B. (eds) Translational Control in Biology and Medicine (CHSL ...
AST, aspartate aminotransferase; APOA, apolipoprotein A; HDL, high-density lipoprotein cholesterol; LDLD, low-density lipoprotein direct cholesterol; CHOL, total cholesterol; HBA1C, glycosylated hemoglobin; AML, acute myeloid leukemia; MDS, myelodysplastic syndromes; CMML, chronic myelomonocytic leukemia. ...