Beta-naphthylamine (BNA) and N-2-naphthylaniline (PBN), are reported as low-level contaminants of PAN. Thermally degraded complex mixture When oils are exposed to high temperatures in the engines or APU, a complex mixture of thermally degraded (thermolysis) components is produced. This includes ...
Conclusions: These results demonstrate the development of a novel mouse with conditional expression of Rgs2 and illustrate the role of Rgs2 within selected cell types for cardiometabolic control. ? 2021 American Heart Association, Inc.doi:10.1161/HYPERTENSIONAHA.122.20169Ritter M.L....
The main driver for the success of modern neonatology was the overarching aim to reduce preterm infant mortality rates. In the last decades, this goal has been achieved in many high-income countries mainly due to the significant progress in the perinatal management of high-risk pregnancies and th...
Increasing urinary podocyte mRNA excretion and progressive podocyte loss in kidney contribute to the high risk of long-term renal disease caused by preterm birth Article Open access 19 October 2021 Acute kidney injury decreases pulmonary vascular growth and alveolarization in neonatal rat pups Artic...
The population-wide reduction in dietary salt and replace- ment of dietary saturated fat (SFA) with polyunsaturated fat (PUFA) are essential in reducing CVD incidence. Their importance is mediated at least in part by the effect of salt on blood pressure (BP) and dietary fat quality on total...
as well as cholesterol. Seafood is praised as an excellent source of protein, yet this nutrient is a false idol of nutrition, as most Americans eat twice the quantity they need in their diets. Consumption of animal protein is associated with several adverse health outcomes including cancer and ...
For qPCR analyses on the ABI PRISM 7900HT Sequence Detection System (Applied Biosystems; see Supplementary Table S1 for primer sequences), cDNA was generated with the High-Capacity cDNA Reverse Transcription kit (Applied Biosystems). RNA sequencing of 500 ng RNA per sample was performed as ...
It is highly likely that commonly used medications might impact the behavior of (metastatic) cancer cells due to the cancer cells’ high non-genetic cellular plasticity (Yuan et al., 2019). To identify drugs that could impact cellular plasticity, we adapted a previously established multiplexed ...
These patients with more severe COPD are almost twice as likely to die of cardiovascular causes than those with less severe disease.34 Four independent clinical variables for concomitant heart failure in COPD can be measured in the primary care setting: history of ischaemic heart disease, high ...
Bone morphogenetic protein 9 (BMP9), also called Growth differentiation factor 2 (GDF2), is a circulating protein that binds with high affinity to activin receptor-like kinase 1 (ALK1), a type I receptor of the TGFβ receptor family, that is important for blood vascular development31. BMP...