The height of each letter is made proportional to its frequency, and the letters are sorted so the most common one is on top. The height of the entire stack is then adjusted to signify the information content of the sequences at that position. From these 'sequence logos', one can ...
sented in bits of information by using sequence logo graphics to represent the average of a set of sites and sequence walker graphics to represent individual sites. “All models are wrong but some are useful.” —George E. P. Box (Box, 1979) ...
In and , a is a way of representing the results of a multiple , where related sequences are compared to each other, and similar functional are found. The consensus sequence shows which residues are conserved (are always the same), and which residues are variable. Developing software for is...
Eukaryotic autonomously replicating sequences (ARSs) are composed of three domains, A, B, and C. Domain A is comprised of an ARS consensus sequence (ACS), while the B domain has the DNA unwinding element and the C domain is important for DNA-protein interactions. In Saccharomyces cerevisiae...
putida. In this study we aimed to determine the ColR binding consensus sequence and to use it in the screen of P. putida genome for the presence of new potential ColR binding sites, which would predict new ColR target genes and operons....
As an example, the EVH1 domain in Ena/VASP proteins bind to FPPPP amino acid sequences present in several interactors (Ball et al., 2000). There are four different families of EVH1 domains, WASP, SPRED, Homer, and Ena/VASP, that bind to distinct proline-rich sequences (Peterson and ...
Sequence logos are stacked bar graphs that generalize the notion of consensus sequence. They employ entropy statistics very effectively to display variatio... F Eva,M Vincent,DH Ardell - 《Nucleic Acids Research》 被引量: 35发表: 2006年 Global food security: assessing trends in view of guiding...
Using custom software, the sequences are aligned relative to the phosphorylated amino acid at position 0, and an information-theoretic algorithm is used to generate position-weighted matrices. Amino acids enriched relative to background at specific positions are displayed using sequence logos. Using ...
Aligning homologous non-coding RNAs (ncRNAs) correctly in terms of sequence and structure is an unresolved problem, due to both mathematical complexity and imperfect scoring functions. High quality alignments, however, are a prerequisite for most consens
If we are able to manage a transition to a sustainable future, we will look back on the sequence of events in that one month: the election of Barack Obama as president of the USA, the World Economic Forum summit on the global agenda, the Club of Rome conference on the inter-connected ...