Matrix attachment regions (MARs) can enhance transgene expression levels and maintain stability. However, the consensus sequence from MARs and its functional analysis remains to be examined. Here, we assessed a possible consensus sequence from MARs and assessed its activity in stably transfected Chinese...
volume 1, pp 457–458, © 2001, Elsevier Inc. Glossary Degenerate consensus sequence A consensus sequence where each position is denoted by a single letter stating allowed or disallowed letters at
Conservation score of a consensus sequence, returned as a double. Scores are computed with the scoring matrix"BLOSUM50"for amino acids or"NUC44"for nucleotides. Scores are the average euclidean distance between the scored symbol and theM-dimensional consensus value.Mis the size of the alphabet. ...
Two search algorithms designed to extract conserved motifs from either aligned or non-aligned sequences independently discovered three sites constituting a common pattern in all seven promoters. Sites were optimally aligned using weight matrix building trials to achieve the maximum 'information content'. ...
Weight matrix descriptions of four eukaryotic RNA polymerase II promoter elements derived from 502 unrelated promoter sequences. Optimized weight matrices defining four major eukaryotic promoter elements, the TATA-box, cap signal, CCAAT-, and GC-box, are presented; they were derived ... P Bucher ...
The matrix-valued weighted Laplacian matrix of a matrix-valued weighted directed graph GG is defined as Ls=Cr−ALs=Cr−A. Analogously, a directed path in a matrix-valued weighted directed graph GG is a sequence of directed edges in the form of (i1,i2),(i2,i3),…,(ip−1,ip)(...
These perform a sequence of elementary tree operations to obtain at each step, in a greedy fashion, a dendrogram that is as close as possible to the given ones. The time and the space complexities of such procedures make them suitable for large scale applications. A numerical example is used...
sequenceconsensus= ''consensus=consensus+"A"=consensus+ 'A' elif 浏览3提问于2016-11-10得票数0 1回答 如何为每行存储和使用csv文件中的两个变量 、 A.csv的每一行的示例home/RUN119_*/analyse/2071436273_*_*/*consensus.fastahome/RUN120_*/analyse/2 ...
Matrix representations also provide an efficient method of aligning multiple sequences to identify binding site patterns that they have in common. 展开 关键词: amino acid sequences, binding sites, computer analysis, sequence alignment, DNA, nucleotide sequences, transposons, matrices, regulatory sites...
We created an siRNA library in the pHUMU vector using partially randomized sequences targeting the consensus region in the ZnF_C4 signature motif of the nuclear hormone receptors and thus against the entire receptor superfamily. For proof of principle, we adapted a reporter assay to screen this ...