Interstitial lung diseaseConnective tissue diseaseCollagen vascular diseaseConnective tissue disease, also referred to as collagen vascular disease, encompasses a group of systemic inflammatory disorders characterized by autoimmune-mediated end-organ damage. Connective tissue diseases may result in a variety of...
Connective tissue disease-as- sociated lung disease. Immunol Allergy Clin N Am. 2012; 32: 513-36.Olson AL, Brown KK, Fischer A. Connective tissue disease-associated lung disease. Immunol Allergy Clin N Am 2012;32:513e36.Olson AL, Brown KK, Fischer A. Connective tissue disease-associat- ...
Connective tissue diseases (CTDs) (also referred to as collagen vascular diseases [CVDs], because collagen is typically affected, and there may be a vascular component) are a heterogeneous group of disorders characterized by the presence of autoantibodies, such as systemic sclerosis (SSc), rheumatoi...
Connective Tissue Disease-associated Interstitial Lung Disease: A review. Curr Respir Care Rep 2012; 1 :224-32.Gutsche, M, Rosen, GD, Swigris, JJ (2012) Connective tissue disease-associated interstitial lung disease: a review. Curr Respir Care Rep 1: pp. 224-32...
Interstitial lung disease (ILD) in connective tissue disease (CTD) is characterized using the classification of the idiopathic interstitial pneumonias. Systemic sclerosis is most frequently associated with ILD and, in most of these patients, ILD manifests as a histological pattern of nonspecific ...
Management of a patient with connective tissue interstitial lung disease (CTD-ILD) depends on disease severity with a focus on improving quality of life. Therapeutic interventions include medications, which aim to prevent progression to fibrosis and decrease inflammation or alveolitis, supplemental oxygen...
Connective tissue diseases: Bosentan treatment unable to alter the progression of interstitial lung disease in patients with SScNature Reviews Rheumatology 6, 309 (2010). doi:10.1038/nrrheum.2 ...doi:10.1038/nrrheum.2010.74Katrin LeggNature Reviews Rheumatology...
Connective tissue disease can sometimes cause serious and deadly health problems, such as: High blood pressurein your lungs (pulmonary hypertension) Lung scarring (interstitial lung disease), which makes it hard to breathe Heart disease (your heart may become enlarged or inflamed, which can lead ...
Castelino Flavia V,Varga John.Interstitial lung disease in connective tissue diseases: evolving concepts of pathogenesis and management. Arthritis research & therapy . 2010Castelino F V, Varga J. Interstitial lung disease in connective tissue diseases: Evolving concepts of pathogenesis and manage- ment ...
Interstitial lung disease (ILD) is common in connective tissue disease (CTD) and is the leading cause of mortality. Investigators have used certain outcome measures in randomized controlled trials (RCT) in CTD-ILD, but the lack of a systematically developed, CTD-specific index that captures all ...