Growing understanding of the key pathogenic drivers of lung fibrosis might lead to the development of more effective targeted therapies to replicate the treatment advances in other aspects of these diseases. Interstitial lung disease (ILD) in connective tissue disease (CTD) is characterized using the ...
Efficiency in follow-up immunology testing for patients with connective tissue diseases and vasculitis.The NHS is under significant financial stress and there is an important responsibility to make savings when possible. Immunology tests, including autoantibody testing and measurement of immunoglob-ulins,...
Autoantibodies are a hallmark feature of Connective Tissue Diseases (CTD). Their presence in patients with idiopathic interstitial lung disease (ILD) may suggest covert CTD. We aimed to determine the prevalence of CTD autoantibodies in patients diagnosed with idiopathic ILD. Methods 499 patient sera ...
activity that is influential in tissue repair and tissue engineering, pharmaceutical compositions can now be developed and used in order to treat skeletal trauma, skeletal development abnormalities (both non-metabolic bone diseases and metabolic bone diseases), arthritis and degenerative joint diseases. ...
Connective tissue growth factor: A fibrogenic master switch in fibrotic liver diseases. Liver Int. 2008, 28, 1065–1079. [Google Scholar] [CrossRef] [PubMed] Pi, L.; Robinson, P.M.; Jorgensen, M.; Oh, S.H.; Brown, A.R.; Weinreb, P.H.; Trinh, T.L.; Yianni, P.; Liu, C...
Keywords: tissue engineering; interstitial; connective; vascular; nervous; visceral; musculoskeletal; polymers; hybrid; hydrogels; layer-by-layer; cells 1. Introduction Except for the gut epithelium [1], cornea [2], skin [3], and liver [4], regeneration of adult tissue after an injury or ...
“This approach could be expanded to look at other pathways we know are important in inflammation, or alternatively, it could be completely unbiased and look for any shared variation that occurs across undiagnosed patients with inflammatory diseases. I think that one thing that’s importa...
Barts and The Royal London NHS Trust—Rheumatology Bancroft Road Stepney Green London E1 4DG UKRheumatologyPyne D, Chaabo K (2007) Adherence to immunosuppressant drugs in patients with connective tissue diseases [letter]. Rheumatology 46(12):1859...
New hydroxamic acid derivatives useful for the treatment of diseases related to the degradation of connective tissueThey refer to a formula compound,Among them, ` X 'is CH2 or NR5, among others; ` y' is CH2 or NR5; ` x'e 'and' y 'are preferably composed of 2-pirolidinona, hidanto...
International Journal of Molecular Sciences Article Activin A-Smad Signaling Mediates Connective Tissue Growth Factor Synthesis in Liver Progenitor Cells Ze-Yang Ding 1, Guan-Nan Jin 1,2, Wei Wang 1, Yi-Min Sun 1, Wei-Xun Chen 1, Lin Chen 1, Hui-Fang Liang 1, Pran K. Datta 3, Ming-...