In medicine, mixed connective tissue disease (also known as Sharp's syndrome), commonly abbreviated as MCTD, is an autoimmune disease, in which the body's defense system attacks itself. It was characterized in 1972. It is sometimes equated with the term "Undifferentiated connective tissue disease...
mixed connective tissue disease 混合结缔组织病 myopathy of connective tissue disease 结缔组织病性肌病 arthritis of connective tissue disease 结缔组织病性关节炎 connective tissue n. 结缔体素,结缔组织 collagenic connective tissue 胶原结缔组织 electric connective tissue 电结缔组织 connective tissue sh...
Mixed connective tissue disease primarily on the basis of a certain period of the prominent clinical manifestations of different drugs. 混合性结缔组织病的治疗主要根据某一时期的突出临床表现采用不同药物。 943g.com 3. Therefore, it was suggested that mixed connective tissue disease is not an independe...
Related to Mixed connective tissue disease: polymyositis, Undifferentiated Connective Tissue Diseasedis·ease (dĭ-zēz′) n. 1. An abnormal condition of a part, organ, or system of an organism resulting from various causes, such as infection, inflammation, environmental factors, or genetic defect...
Mixed connective tissue disease (MCTD), or: Sharp syndrome, is an uncommon, specifically defined, overlap syndrome. MCTD should be suspected when additional overlapping features are present in patients appearing to have rheumatoid arthritis, SLE, scleroderma, or polymyositis. MCTD is characterise...
Mixed connective tissue disease (MCTD) was first described by Gordon Sharp,1 in 1972, as a distinct connective tissue disorder characterized by overlapping features of systemic lupus erythematosus (SLE), progressive systemic sclerosis (PSS), and dermato/polymyositis (DP/PM). This can be distinguishe...
HLA type as a predictor of mixed connective tissue disease differentiation. Ten-year clinical and immunogenetic followup of 46 patients. Objective. To determine any clinical or genetic markers of differentiation and outcome in a previously described cohort of 46 patients with mixed connective tissue ...
The National Institutes of Health stipulated a survival rate of 10years for 80% of people with MCTD. That is, about 80% of persons with the disease will still be living 10years after diagnosis. Symptoms of Mixed Connective Tissue Disease (MCTD) ...
Signs and symptoms of mixed connective tissue disease can include rash, muscle pain, joint pain, swollen fingers, swollen hands, and malaise. Other associated symptoms and signs can include low-grade fever and Raynaud's phenomenon (sensitivity, numbness, and loss of color in the fingers, toes,...
Mixed Connective Tissue Disease . Figure 1 The U1-RNP complex is composed of the specific U1-RNA stem as well as three specific protein subunits known as the A, C, and 70 kD subunits. Another group of proteins in this structure, ... 展开 ...