Fischer U, Freyse EJ, Salzsieder E, Rebrin K: Artificial connection between glucose sensing and insulin delivery: implications of peritoneal adminis- tration. Artif Organs 16:151-162, 1992Fischer U, Freyse EJ, Salzsieder E, et al. Artificial connection between glucose sensing and insulin ...
We don't know all the mechanisms, but we do know that patients who are diagnosed with a first episode of schizophrenia—before they've even been treated with medications—already have disrupted insulin and glucose metabolism in the brain. As insulin resistance develops, the brain becomes "leakier...
While inflammation and its subsequent extension into the brain is the main mediator of obesity-associated neurological issues, other mechanisms, such as insulin resistance, oxidative stress, and dysfunction of cellular organelles, may also play a role [1]. Overeating and obesity change ...
Some of these features, such as insulin resistance, impaired glucose metabolism, and deregulation of O-GlcNAcylation, may serve as molecular links between T2DM and AD. Research on these molecular links is reviewed and discussed in this chapter. Understanding of these molecular links will help ...
Insulin sensitivity (M-value) was estimated by the euglycemic hyperinsulinemic glucose clamp method. Fatty acid-binding protein (FABP) in skeletal muscle was measured by ELISA, and the expression of FABP mRNA was analyzed by semi-quantitative RT-PCR. The serum and muscle triglyceride (sTG and ...
Your metabolism isn’t geared towards processing food efficiently at night when it should be sleeping. Eating late at night, especially sugary or carb-rich foods this time of night when cells are more insulin resistant, causes higher and more variable glucose levels, and storage o...
High blood sugar levels can damage blood vessels over time, leading to complications like heart disease and an increased risk of Alzheimer’s disease. Insulin resistance, often associated with diabetes, also may impact the brain’s ability to utilize glucose efficiently, which can lead to impaired...
Deficiency in chromium can lead to symptoms such as impaired glucose tolerance, increased insulin resistance, and poor blood sugar control. Malabsorption of chromium can occur in celiac disease due to damage to the small intestine lining, potentially leading to a deficiency. Supplementation o...
The underlying correlative mechanisms between Insulin resistance (IR) and recurrent pregnancy loss (RPL) in patients without polycystic ovarian syndrome (PCOS) remain inconclusive. To investigate the association between triglyceride (TG) levels, lymphocyte subsets, and IR in RPL patients without PCOS and...
Glucose transporter HPX: Hypoxanthine HUVEC: Human umbilical vein endothelial cell IRS: Insulin receptor substrate JNK: C-Jun N-terminal kinase MAPK: Mitogen-activated protein kinase MCT: Monocarboxylate transporter MRP: Multidrug resistance-associated protein ...