Widely studied in a chemical context, such chromophores are inherently bioincompatible due to their highly lipophilic character. Attachment of two polycarboxylate dendrimers, a method we call "cloaking", to a bisstyrylthiophene (or BIST) core effectively transformed the chromophore into a water‐...
In fact, the (bio)conjugation field has particularly advanced at an astonishing pace in the last decades. Instead of being exhaustive, here we aimed to present the basic toolbox that is currently available to a researcher to move in the (bio)functionalization area, particularly focusing on ...
View bio Instructor Elena Sacramento Lechado View bio Learn about the Spanish verb hacer, meaning "to do" or "to make," and its conjugation. Examine forms of hacer in the preterite, subjunctive, and imperfect tenses.Updated: 11/21/2023 ...
In spite of the tremendous experimental and bio- informatics efforts that have taken place in the past 15 years, the annotation of E3 ligases that are associ- ated with human disease is still in its infancy. The RING finger ligases alone constitute one of the largest enzyme groups in the ...
Progressive disruption of cellular protein folding in models of polyglutamine diseases. Science. 2006;311:1471–4. Article CAS Google Scholar Cummings CJ, Reinstein E, Sun Y, Antalffy B, Jiang Y-H, Ciechanover A, et al. Mutation of the E6-AP ubiquitin ligase reduces nuclear inclusion ...
In spite of its high selectivity and mild reaction condition, the click chemistry-based conjugation requires a “clickable” group to be added to a polymer prior to its immobilization. The additional reaction step increases the complexity of material synthesis and is often difficult to accomplish. ...
aPara saber 巴拉军刀[translate] aCity of hot sales throughout the city 热的销售城市在城市中[translate] aThe Franchisee must ensure that each Station has a public telephone in operating order,unless otherwise agreed with PTV. 特许经营者必须除非经同意保证每个驻地有一个公用电话按经营的顺序,与PTV。
The regulation of protein fate by modification with the small ubiquitin-related modifier (SUMO) plays an essential and crucial role in most cellular pathways. Sumoylation is highly dynamic due to the opposing activities of SUMO conjugation and SUMO decon
These accessible bio- molecules are targets for pathogen specific vaccination. Glycoconjugate vaccines that combine a glycan antigen with a carrier protein have for the most part replaced polysaccharide vaccines that fail to induce a strong immune response2 and do not result in B-cell memory in ...
The capacity of LPs to transport hydrophobic molecules, the lipid nature of squalene as well as its bio-relation to cholesterol altogether led us to believe that the interaction between the SQGem NPs and LPs deserved to be deeply explored. In the present study, we demonstrate that SQGem ...