Although the diagnosis of congenital FVII deficiency is straightforward with isolated prolonged prothrombin time (PT) and decreased FVII level, differential diagnosis of acquired FVII deficiency should be considered. Several therapeutic options such as fresh frozen plasma (FFP), plasma-derived FVII (pd-...
Homozygous congenital factor VII deficiency with a novel mutation, associated with severe spontaneous intracranial bleeding in a neonate Objective:Herein, a neonate with congenital FVII deficiency is presented. Basic method:Diagnosis of congenital FVII deficiency was confirmed by genetic ana... S Kader,...
Congenital factor VII (FVII) deficiency is a rare bleeding disorder with autosomal recessive inheritance. The present female patient was diagnosed with congenital FVII deficiency because of low hepaplastin test (HPT), although vitamin K was given. Heterozygous p.A191T mutation was detected in the ...
4.Therapeutical Options for Congenital FVII Deficiency The HK 7 Project of the International Greifswald Registry of the Congenital FVII Deficiency (GR-HK-7) and spring 机译:先天性FVII缺乏的治疗方案,先天性FVII缺陷国际格雷夫瓦尔德注册管理机构HK 7项目(GR-HK-7) F. H. Herrmann ,G. Auerswald ,J...
Though the diagnosis of congenital FVII deficiency is straightforward due to isolated prolonged prothrombin time (PT) and decreased FVII level, the differential diagnosis of acquired FVII deficiency should be also bear in mind. Several therapeutic options such as fresh-frozen plasma (FFP), plasma-...
Recombinant activated FVII (rFVIIa, NovoSeven(R)), the first recombinant treatment option, has recently been approved in the European Union for use in congenital FVII deficiency, but has been available on an emergency and compassionate use basis since 1988. In FVII deficiency, rFVIIa serves as ...
Congenital factor VII (FVII) deficiency is the most common of the rare bleeding disorders with an autosomal recessive pattern of inheritance and a prevalence of 1/500 000. During the several decades after the first description of the disease in 1951, only a limited number of patients has been...
Congenital factor VII deficiencyBackground and Objective: Factor VII (FVII) deficiency is probably one of the most common of the rare autosomal recessive coagulation disorders, with an estimated prevalence of l: 500000. All age groups can be affected with FVII deficiency. This study aimed to ...
We report a case of congenital FVII deficiency in a patient aged 22 years, who underwent surgical treatment of nephrolithiasis. FVII deficiency was 22%, no replacement therapy was introduced to the patient, and no bleeding complications were observed in intraoperative or postoperative. In conclusion,...
Girolami A, Berti de Marinis G, Vettore S, Girolami B. Congenital FVII deficiency and pulmonary embolism: a critical appraisal of all reported cases. Clin Appl Thromb Hemost 2013;19:55-9.Girolami A, Berti de Marinis G, Vettore S, Girolami B. Congenital FVII deficiency and pulmonary ...