The activities of cold-responsive C-repeat-binding transcription factors (CBFs) are tightly controlled as they not only induce cold tolerance but also regulate normal plant growth under temperate conditions1–4. Thioredoxin h2 (Trx-h2)—a cytosolic redox
Interestingly, we observed a greater fold change for DCK (3.1-fold, MiaPaCa and 2.6-fold, Colo-357) at protein level (Supplementary Figure 4) relative to that at the transcript level (Figure 3A). We next examined whether the differential expression of CAT, SOD2 and DCK was sustained for ...
we focused our attention onDCK, whose expression was decreased in Gem-Exo-treated PC cells. We first investigated the mechanism that causedDCKdownregulation in Gem-Exo-treated PC cells as no DCK transcript was detected in exosomes from either vehicle or gemcitabine-treated PC cells (Supplementary F...
In this study, genome-wide sequencing yielded a broad set of can- didate genes. A total of 132 genes were found to have non-synonymous amino acid mutations in the resistant strain YP-1 relative to the F. graminearum reference strain PH-1. Because more than half of the mutated genes ...
This mutation led to the formation of at least four kinds of splicing variants of SLG1 in the mutant, which were confirmed by sequencing, and no normal SLG1 transcript was found in the mutant. The primer set used for amplifying the splicing variants is listed in Supplementary Data 3. ...