The light green area represents the site and the extension of subretinal injection. (a, middle panel) Assembly of black and white fundus images showing dome-like retinal bleb following subretinal injection of 100 ml of AAV vector containing- solution. The asterisk indicates the injection site. (...
In addition, in silico assessment of the c.499+1G>T and c.499+5G>A mutations via two distinct web-based platforms, NNSPLICE 0.910 and Human Splicing Finder,11 predicted for both variants the abolishment of the donor splicing site for intron 3. To analyze the functional consequences of the...
Recent success in clinical trials supports the use of adeno-associated viral (AAV) vectors for gene therapy of retinal diseases caused by defects in the retinal pigment epithelium (RPE). In contrast, evidence of the efficacy of AAV-mediated gene transfer to retinal photoreceptors, the major site...
Assessment of ocular transduction using single-stranded and self-complementary recombinant adeno-associated virus serotype 2/8. Gene Ther 2008; 15: 463–467. Article CAS PubMed Google Scholar Alexander JJ, Umino Y, Everhart D, Chang B, Min SH, Li Q et al. Restoration of cone vision in a...
In addition, a complete closure of the post-resection defect with flaps makes clinical examinations difficult in proper assessment of the postoperative field for local recurrence. In these cases, oncological follow-up is based on computed tomography (CT) or magnetic resonance imaging. In addition, ...
Cone calorimeter is a widely used device to measure fire reaction properties, in fire potential assessment of wood, polymer, and even for batteries. Fu's paper concerning cone calorimeter tests of lithium ion batteries indicates that the collected data can be used directly, as well as input ...
Monitoring is carried out by the Center for Surveying and Assessment of Agriculture and Natural Resources (http://www.crean.unc. edu.ar/monitoreo-de-sequias/), in cooperation with the Secretary of Environment and Sustainable Development and the Nacional Meteorological Service. Statewide monitoring is...
Materials and Methods: A total of 1450 initial patients diagnosed with maxillary sinusitis in the Ear-Nose-Throat (ENT) Department, University of Medicine and Pharmacy “Grigore T. Popa” Iasi, Romania, were treated with anti-inflammatory drugs. Of these, 629 still had unresolved symptomatology ...