l‐Methionine γ‐lyase (MGL) is a PLP‐dependent enzyme which catalyzes the α, γ‐elimination reaction in sulfur containing amino acids, such as L‐methionine and L‐cysteine. Its major applications are on metabolic restriction of methionine to cancer cells, food industry (che...
The effects of the operation parameters such as reaction temperature, reaction pressure, H_2/ paraffins volume ratios and space velocity on the behavior of Pt-Sn-K/γ-Al_2O_3 dehydrogenation catalyst was investigated using the dehydrogenation of long-chain paraffins (C_(l7)-C_(20)) as the...
molecules Review Novel Methodologies for Chemical Activation in Organic Synthesis under Solvent-Free Reaction Conditions Claudia Gabriela Avila-Ortiz 1,* and Eusebio Juaristi 1,2,* 1 Departamento de Química, Centro de Investigación y de Estudios Avanzados, Av. IPN 2508, 07360 ...
with high graphitization degree,which resulted in the decreasement of the wear rate.C/C composites by CLVI process can fairly meet the demand for the performance of wet friction materials,and the manufacture cost is low in comparison with traditional chemical vapor infiltration for C/C composites....
The influences of electron-withdrawing groups and of the location of the heteroatom substituent relative to the halide are discussed. Suitably substituted ORTHO-amino dehydrophenylalanine derivatives undergo a cyclization-elimination reaction to the corresponding 2-substituted indoles....
To examine this possibility, we investigated the kinetics of the reaction under biological conditions and determined the second order rate constantas 2.360±0.198Ms. We then calculated the time required for HOelimination by pyruvate. The results show that, with an average intracellular concentration of...
Dep.TadaakiDep.OhgiyaDep.ShigeruDep.NishiyamaDep.WileyCheminformKutsumura N., Yokoyama T., Ohgiya T. and Nishiyama S. (2006). 1, 2-Dibromoalkanes into alkynes by elimination reaction under DBU conditions and their application to total synthesis of sapinofuranone B. Tetrahedron letters, 47(25),...
with an effective rate constantVmax/Km, while at large substrate concentrations the reaction saturates at its maximum rateVmax. For a fixed amount of enzymeET, the analysis of the role of the velocity of each reaction in the emergence of signal termination reduces to the analysis ofk/Km,andk...
The metal-promoted activation of the normally inert carbon-fluorine bond in saturated fluorocarbons usually involves stronglyreducting conditions with conversion of fluorine to a metal fluoridesalt providing much of the driving force for reaction. The Achillesheel of many saturated fluorocarbons, such as...
A simple and efficient Ru-catalyzed conjugate addition reaction of arylboronic acids to α,β-unsaturated ketones under neutral conditions without any additional ligands has been developed. This Ru(II)-catalytic system both fulfilled the inhibition of the β-hydride elimination in the catalytic cycle ...