Advanced cultivation methods, genomics- and metagenomics-based approaches, as well as modern metabolomics-inspired methods are highlighted to emphasise the interplay of different disciplines to improve access to novel natural products. Keywords: metagenomics; rare actinomycetes; dereplication; metabolomics; ...
Recent tools for synthetic biology and current attempts to engineer new codes for incorporation of non-standard amino acids are also reviewed in this article. Keywords: genetic code; evolution; codon reassignment; amino acids; biotechnology 1. Introduction The genetic code maps 64 codons onto a set...