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delivery of services,theconcept of system-widecoherence was still under consideration by the General Assembly. daccess-ods.un.org daccess-ods.un.org 在区域一级的全系统一致性方面,有人表示,“一体行动”是一个旨在改 进提供服务效率的秘书处内部政策,而这个全系统一致性概念仍在大会的审议之中。
To confirm the feasibility of sequence-to-drug concept, we compared TransformerCPI2.0 with conventional structure-based drug design approaches to test its ability to screen active molecules from compound libraries. We used the benchmark dataset DUD-E set30 and DEKOIS2.0 set31 and the enrichment fac...
While such processes may similarly be employed to enhance the impact of public health initiatives, optimisation has not been defined in the context of public health and there has been little exploration of its key concepts. Methods: We used a modified, three-round Delphi study with an ...
To alleviate the ‘black box’ problem and gain insights into the model and its predictions, the field of explainable artificial intelligence (XAI) has been established. In fact, a multitude of XAI methods have been developed that are able to provide explanations of a model’s decision while ...
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We tested whether the chaperones associated with CRAG might be involved in its degradation. CRAG breakdown was accelerated 2-3-fold in strains with high levels of heat-shock proteins (hsps), i.e. in those that overproduce the hsp transcription factor (sigma 32) or carry a dnaK deletion. A...
A The concept of transpathology research and its challenges; B a concept of integrative MIMI system based on an animal model with a dorsal skin window chamber for transpathology investigation, which enables positron imaging, MRI and optical imaging within the same intact framework to allow better ...
(c) HAADF-STEM image of a Rh/SiNW. Scale bar, 50 nm. (d) Its corresponding EDS mapping showing the O, Si and Rh distributions. EDS, energy dispersive spectroscopy; HAADF-STEM, high-angle annular dark field scanning TEM; HRTEM, high-resolution TEM. Full size image Electrochemical ...
The diversity of somatic mutations in human cancers can be decomposed into individual mutational signatures, patterns of mutagenesis that arise because of DNA damage and DNA repair processes that have occurred in cells as they evolved towards malignancy.