The principle of modularity is a promising approach to personalize psychotherapy; however, to date there is no evidence on how modular-based psychotherapy (MoBa) can be implemented using a systematic treatment algorithm for adult patients. Therefore, in this proof of concept study 70 patients with ...
Those in the low-risk category, who had 60% or higher probability of recovering, entered the NoTx arm; the rest, who had less than 60% probability of recovering naturally, were randomized between a placebo control arm and a pharmacological treatment arm. A flexible dose escalation procedure ...
Second, it does not elaborate clearly about the how and when of evaluation. Show moreView article Review article A review of machine learning algorithms for identification and classification of non-functional requirements Expert Systems with Applications: X Journal2019, Expert Systems with Applications:...
Our proposed RL-DITR as a model-based RL consists of two components: a patient model to characterize the diabetes progressive state by learning the environment’s dynamics and a policy model for management of diabetes by planning with respect to the learned model. Specifically, the patient model ...
Moreover, hypothetical examples and possible algorithms for early discovery/phase I development using neuroimaging provide specific working approaches. In summary, this article reviews the vital biomarker approach of neuroimaging in proof of concept studies. This is a preview of subscription content, ...
Since LLMs and the human brain have been suggested to share similar computational principles for language,51,75,76LLMs can serve as a potential reference in the future to help us understand the actual, rather than hypothetical, language-dependent algorithms that the human brain relies on to infer...
Immuno-oncology has witnessed remarkable advancements in the past decade, revolutionizing the landscape of cancer therapeutics in an encouraging manner. Among the diverse immunotherapy strategies, mRNA vaccines have ushered in a new era for the therapeut
Study participants were randomly assigned to each of these treatment targets in a 5:4:1 ratio, with therapy administered according to a treatment algorithm dependent on each patient’s existing UC treatment regimen at study entry.1 Across all 3 algorithms, early introduction of vedolizumab and...
the pre- and postoperative management of diabetes-related comorbidity, identifying means of sustaining surgery-induced metabolic improvements and the development of postoperative treatment algorithms particularly those for patients with persistent or recurrent disease including the use of long-term ...
A recent meta-analysis on 841 patients across 20 randomized controlled trials (RCTs) demonstrates that rTMS is beneficial to the treatment of post-stroke hemiplegia, especially in: lower limb functioning, grip strength, and attenuating stroke severity16. Interestingly, cortical reorganization can be ...