Results Transcriptome analysis indicates AA-mediated inhibition of cell proliferation and induction of cellular senescence in CRPC cells Transcriptome analysis was performed with the CRPC C4-2 cell line treated with AA or solvent control (DMSO). The gene ontology (GO) gene sets indicate that AA re...
The results of an extensive conservation analysis over more than 3,900 species are shown in Supplementary Fig. S3 and discussed in the text. Full size image Orthogonal validation by Sanger sequencing confirmed the presence of the two variants in the proband. DNA from her father was not ...
This is caused by indirect transition among H point and &boxdr& point and this value is corresponding to the experimental results by Weiher et al. As shown in Fig.5, the absorption edge is red shifted according to the increase of amount of introduction and saturated at over than x=0.5. ...
Our results indicated that pH was a key parameter to control cell growth and morphol- ogy in the cultures and therefore a pH-control strategy was developed, considering pH 6.2 as lower boundary to avoid severe growth inhibition. Since pH shifts in the stirred tanks are realized by addition of...
Methods/results We characterized the clinical, radiological, and cellular features that add to the human MCPH2 phenotype. Exome sequencing followed by Sanger sequencing in a German family with two affected daughters with primary microcephaly revealed in the index patient the compound heterozygous mutation...
Central outcome of our study is the connection between fungal emission patterns and trophic modes. The results suggest that fungal guilds and lifestyles can be grouped according to the fVOC profiles. Knowing that some fungi are able to change their trophic modes, care should, however, be taken ...
These results show that the combination of BV10 with CDDP indeed led to a significant enhancement in the formation of DNA DSBs. Figure 2 Cellular DNA DSB measurements in different cancer cell lines using γH2AX labeling. Representative pictures of γH2AX labeling are shown in (A), (C) and ...
Activation of NF-κB results in increased secretion of inflamma- tory cytokines such as interleukin (IL)-89–11, which recruit inflammatory cells, including neutrophils5. Moreover, ROS trigger the peroxidative breakdown of lipids, a process implicated in lung injuries due to increased airway ...
testing, manuscript preparation; URA contributed to isolation and structure elucidation of SF2446A2, manuscript preparation; AB and TQ contributed to antischistosomal activity testing, manuscript drafting; TR, CGG and UH contributed to manuscript preparation, analysis of assay results, revising the ...
The lower quantities of silver improve the optics of the elements, thus enabling the production of sharper pictures using the elements. These lower quantities of silver are additionally important in that they enable rapid development and desilvering of the elements. Conversely, a silver coating ...