The first is an EI workflow that can be used to find biomarkers through statistical analysis and identify unknown compounds via library search, and the second is a CI workflow that can identify unknown compounds
The first is an EI workflow that can be used to find biomarkers through statistical analysis and identify unknown compounds via library search, and the second is a CI workflow that can identify unknown compounds of interest through molecular formula determination and structural elu...
In the past decade, this situation has led to the development of various algorithms that attempt to infer compound identity directly from mass spectra, so-called in silico methods. These include, but are not limited to, CSI:FingerID as part of the SIRIUS suite5,6, MS-FINDER7,8, and MS2L...
During the inference stage, users can query PertKGE with a compound or target of interest, depending on their objective, such as target inference or ligand virtual screening (VS). Following the query, PertKGE calculates the CPI scores using the trained KGE and generates a recommended list based...
Here, we have applied deep metagenomic sequencing and metaproteomic analyses to sub-root zone samples from a grassland soil ecosystem from a Mediterranean climate. Mediterranean grassland soils are of particular interest as they have not been genomically characterized and undergo strong seasonal drying and...
The first is an EI workflow that can be used to find biomarkers through statistical analysis and identify unknown compounds via library search, and the second is a CI workflow that can identify unknown compounds of interest through molecular formula determination and structural elucidation of MS/MS...
4E). There was also no effect of CBK77 on the activity on USP7 [26, 27], USP14 [28], and UCH-L5 [6], three DUBs that we considered of specific interest as these have been found to be targeted by other experimental compounds (Fig. 4F). Thus, CBK77 causes a global impairment ...
The first is an EI workflow that can be used to find biomarkers through statistical analysis and identify unknown compounds via library search, and the second is a CI workflow that can identify unknown compounds of interest through molecular formula determination and ...
The first is an EI workflow that can be used to find biomarkers through statistical analysis and identify unknown compounds via library search, and the second is a CI workflow that can identify unknown compounds of interest through mo...
The first is an EI workflow that can be used to find biomarkers through statistical analysis and identify unknown compounds via library search, and the second is a CI workflow that can identify unknown compounds of interest through molecular formula determination and structural elucidation of MS/MS...