1. A method of treating a Central Nervous System (CNS) disorder in a pediatric patient in need thereof, the method comprising: measuring cytokine levels in a cerebrospinal fluid (CSF) sample from the pediatric patient, and comparing the patient sample levels to a first reference sample, wherein...
in which the meaning of R'' is the same as above with the difference here that the carbon atom connecting to the OH group can only be primary or secondary, in the presence of chromium trioxide, a suitable organic solvent, acetic anhydride and an acid at temperatures between -60 and -30...