Similar to the genes enriched at the LE, those in group 4–6 show high dysregulation, with a large proportion downregulated and a few aberrantly upregulated. Overall, the transcriptome profile at the LE differs greatly from region- and age-matched healthy cortex, indicating a complex ...
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Centanni, M., Sims, I. M., Bell, T. J., Biswas, A. & Tannock, G. W. Sharing a β-glucan meal: transcriptomic eavesdropping on a Bacteroides ovatus-Subdoligranulum variabile-Hungatella hathewayi consortium. Appl. Environ. Microbiol. 86, e01651-20 (2020). Article ADS CAS PubMed Pub...
5 SIMS AVENUE CONCOURSE LEVEL - NEAR UOB ATM (S) 387405 SAM STATION (S014) APPROX. 1.742 KM AWAY 101 TOWNER ROAD#01-204/206 (S) 322101 SAM STATION (S012) APPROX. 1.751 KM AWAY 447 GEYLANG ROAD (S) 389406 SAM STATION (S748) APPROX. 1.779 KM AWAY 171 PAYA LEBAR ROAD, CONCOU...
As the prevalence of multi-morbidity increases in ageing societies, health and social care systems face the challenge of providing adequate care to persons with complex needs. Approaches that integrate care across sectors and disciplines have been increa
Rowlands G, Sims J, Kerry S: A lesson learnt: the importance of modelling in randomized controlled trials for complex interventions in primary care. Fam Pract. 2005, 22: 132-139. 10.1093/fampra/cmh704. Article Google Scholar Lewin S: Mixing qualitative and quantitative methods in complex hea...
Sims RJ 3rd, Rojas LA, Beck D, Bonasio R, Schuller R, Drury WJ 3rd et al. The C-terminal domain of RNA polymerase II is modified by site-specific methylation. Science 2011; 332: 99–103. Article CAS Google Scholar Zhang DW, Rodriguez-Molina JB, Tietjen JR, Nemec CM, Ansari AZ ...
Figure 4 DNA methylation alterations are enriched in functional promoters and enhancers. (A)Four DNA methylation state patterns across embryonic stem cells (H1), normal endometrium (NE), and endometrial cancer (EC). Red block: methylated state; empty: unmethylated state.(B)Fractions of DMRs with...
Visualization of the electrolyte migration under electrochemical process by ToF-SIMS. Acta Chimi. Sinica 77, 1164–1167 (2019). Article CAS Google Scholar Download references Acknowledgements This work is supported by the National Natural Science Foundation of China (22090050, 21974126, 21874121 and ...
M. & Sims-Mourtada, J. The multifaceted roles of B cells in solid tumors: emerging treatment opportunities. Target. Oncol. 12, 139–152 (2017). Article PubMed Google Scholar Brodt, P. & Gordon, J. Anti-tumor immunity in B lymphocyte-deprived mice. I. Immunity to a chemically induced...