This session featured speakers and panelists from both the generic industry and the FDA who described applications of advanced quantitative approaches for generic drug development and regulatory assessment within three main topics of interest: (1) API sameness assessment for complex generics, (2) ...
Search PharmaCompass to find CDMOs offering synthesis and development of complex APIs or complex drug substances. Also find various types of complex active ingredients including peptide APIs, mixture of APIs, natural source products, polymeric compounds,
The future of biosimilar patent litigation will be shaped by factors such as increasing product complexity, global harmonization efforts, and advancements in analytical technologies. FAQs Q: What is the difference between a biosimilar and a generic drug?A: While both biosimilars and generic drugs are...
The health industry has always used natural products as a rich, promising, and alternative source of drugs that are used in the health system. Propolis, a natural resinous product known for centuries, is a complex product obtained by honey bees from substances collected from parts of different p...
蛋白别名: 13 kDa differentiation-associated protein; 13kDa differentiation-associated protein; 14.5b subunit of the NADH-ubiquinone dehydrogenase complex; 16 kDa precursor; 19 kDa; 24-kDa subunit of mitochondrial NADH dehydrogenase; ACP; Acyl carrier protein, mitochondrial; B17.2-lik...
they were rarely found in the top 200 brand name and top 200 generic pharmaceuticals1. While drug candidates may not enter the commercial market for many reasons, synthetic accessibility undoubtedly affects drug discovery and can bias subsequent drug development. Using state-of-the-art chemistry, we...
aAt the preclinical stage of drug development, you must extensively test your product in the laboratory to ensure it will be safe for human administration. We understand that selecting a research and development partner to perform such testing is a complex decision and that the science, communicatio...
The gene expression profiling was performed with the objective to predict tumor recurrence in stage II and stage III colon cancer patients after therapeutic intervention with 5′fluorouracil (5FU)-based adjuvant chemotherapy, which is the most prevalent drug used for CRC treatment. S100A10 was ...
Camptothecin (CPT), an alkaloid with potent anticancer activity, is still not used in clinical practice due to its high hydrophobicity, toxicity, and poor active-form stability. To address these shortcomings, our research focuses on the encapsulation of this drug in the poly(amidoamine) (PAMAM) ...
“Generative AI has the potential to fundamentally change the process of scientific discovery, research and development, innovation, new product and material testing, etc. as well as create new products and platforms.” But the economic impact of historically transformative technologies like AI take ...