Does a complete loss of articular cartilage of patella warrant a patellar resurfacing when combined with patellar denervation in primary total knee arthroplasty? Results of a randomized prospective trialdoi:10.4103/JOASP.JOASP_16_22Swaroop, Shakti...
Orexin-A (OXA), a neuropeptide produced in the hypothalamus, is recognized for its role in modulating orofacial nociception and regulating feeding behavior
The nature of in vivo mechanical signals that influence cartilage health and progression to knee osteoarthritis. Knee osteoarthritis is a disease that can be initiated along multiple pathways that ultimately leads to pain, loss of function and breakdown of the articul... TP Andriacchi,J Favre -...
In a primate model of knee joint chondral damage, we observed that allogeneic induced pluripotent stem cell-derived cartilage organoids exhibited remarkable survival, integration, and remodeling, resembling articular cartilage. The histological evaluation revealed that allogeneic iPSC-derived cartilage organoid...
LN = lymph nodes; IA = articular cartilage. The severity of clinical signs across all groups generally remained mild, with values below 1 for most parameters (Figure 7B). However, in the fifth passage (P5 group), the severity of clinical signs increased, with symptoms such as fever, ...
This causes pain in the extremities, difficult to carry out movements, produces friction between both bones, and damage to the articular cartilage deteriorating the muscles and the joint. So it is considered a degenerative disease. Hip dysplasia is not a congenital disease. It is a disease that...
Complete anterior cruciate ligament tear and the risk for cartilage loss and progression of symptoms in men and women with knee osteoarthritis. Osteoarthritis Cartilage. 2008; 16: 897-902.Amin S, Guermazi A, Lavalley MP, et al. Complete anterior cruciate ligament tear and the risk for ...
Osteoarthritis Cartilage 14:759–768Sondergaard BC, Wulf H, Henriksen K, Schaller S, Oestergaard S, Qvist P. et al. Calcitonin directly attenuates collagen type II degradation by inhibition of matrix metalloproteinase expression and activity in articular chondrocytes. Osteoarthritis Cartilage. 2006; ...