Factor H is an essential regulatory protein that plays a critical role in the homeostasis of the complement system in plasma and in the protection of bystander host cells and tissues from damage by complement activation. Genetic and structural data generated during recent years have been instrumental...
Factor H (FH) is a soluble regulator of the proteolytic cascade at the core of the evolutionarily ancient vertebrate complement system. Although FH consists of a single chain of similar protein modules, it has a demanding job description. Its chief role is to prevent complement-mediated injury ...
Factor英 /ˈfæktə(r)/ 美 /ˈfæktər/ 释义n. 因素;要素;因子 例句This is a factor which we must not neglect.这是一个我们绝不能忽略的因素。 概述 概述 补体的激活途径主要有3条:经典途径、甘露糖结合凝集素(MBL)途径和旁路途径。补体旁路途径中的调节因子包括补体H因子(CFH)、CFH相...
The genetic associations to factor H polymorphisms, the role of factor H in the resolution of inflammation in lipid-rich deposits, modification of macrophage functions, and complement-mediated clearance of apoptotic and damaged cells indicate that the function of factor H is crucial in limiting ...
Factor H, together with its splice variant factor H-likeprotein 1(FHL-1), inhibitscomplement activationat the level of the centralcomplement component C3and beyond. In humans, there are also five factor H-related (FHR) proteins, whose function is poorly characterized. While data indicate ...
Complement factor H (CFH) 来自 Springer 喜欢 0 阅读量: 19 作者: None 摘要: A genotyping study identified a loss-of-function mutation in CFH that could help predict AMD risk. Further details on the research, next steps and licensing status are discussed in the article. DOI: 10.1038/sci...
英文名称: Human Complement factor H ELISA KIT 用途: 补体因子 H 是分子量约为 155kDa 的糖蛋白,能够为补体级联反应的替代途径提供关键负调控作用,该蛋白由 Kupffer 细胞、肝细胞、血管内皮细胞和血小板分泌产生,血清中浓度较高。补体因子 H 由 20 个短保守重复序列(short consensus repeats,SCR)组成,每个序列...
靶标信息 Factor H is a serum protein acting as an inhibitor in the complement activation system. I activates the C3/C5 convertase by dissociating its subunits and also acts as a cofactor for the enzyme activity of Factor I. 仅用于科研。不用于诊断过程。未经明确授权不得转售。相关...
MCE 站:Complement factor H/CFH, Human (HEK293, His) Synonyms: rHuComplement factor H/CFH, His; Complement factor H; CFH Species: Human Source: HEK 293 Biological Activity: Data is not available. 品牌介绍:• MCE (MedChemExpress) 拥有数百种全球独家化合物,我们致力于为全球科研客户提供*新*...
网络补体H因子;补体因子 网络释义 1. 补体H因子 药学杂志电子报99期 ... CFH:complement factor H补体H因子POS:photoreceptor outer segment 光接受器外节 ... www.taiwan-pharma.org.tw|基于2个网页 2. 补体因子 www.dictall.com|基于 1 个网页