在肿瘤缓解率方面,COMPASSION-16研究结果显示卡度尼利单抗组ORR、CR及持续缓解时间(DoR)也得到显著提高,其中ITT人群的ORR为82.9%(vs 68.6%),完全缓解(CR)患者比例为35.6%(vs 22.9%),mDoR为13.2个月(vs 8.2m),再次验证了双抗...
总的来说,COMPASSION-16研究是卡度尼利单抗用于治疗晚期一线复发或转移性宫颈癌的关键性研究,也是继卡度尼利单抗作为二线用药治疗晚期宫颈癌后又一重大突破性进展,该研究结果发布,不仅为卡度尼利单抗一线治疗提供了有力的循证医学依据,...
第二个关注点是贝伐珠单抗与免疫治疗联合使用时的贡献。尽管无法得出明确结论,但COMPASSION-16的事后分析表明,卡度尼利单抗对未同时接受贝伐珠单抗的个体比对接受贝伐珠单抗的个体具有更大优势,无进展生存期的HR为0.46对0.81,总生存期的HR为0.50对0.84。对于不符合贝伐珠单抗使用条件的个体,他们可能更虚弱或有更多合并症,...
COMPASSION-16数据相当惊艳,作为LBA在2024年国际妇科癌症学会全球会议(IGCS 2024)口头报告和荣登《柳叶刀》主刊实至名归!令人印象深刻的是全人群,以及客观缓解率(ORR)82.9%,完全缓解(CR)率35.6%,真的是高!癌症治疗不就是要针对全人群和ORR和CR吗,这么高的ORR和CR率足以傲人。至于哪些不考虑患者基线,不考虑序贯治...
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Compassion is a desire within us to help others.With effort,we can translate compassion into action.An experience last weekend showed me this is true.I work part-time in a supermarket across from a building for the elderly.These old people are our main customers,and it's not hard to lose...
11 Lord, you do not[a] withhold your compassion from me.Your constant love and truth will always guard me. Read full chapter Footnotes 40:11 Or Lord, do not Psalm 40:11 in all English translationsPsalm 69:16 Christian Standard Bible 16 Answer me, Lord,for your faithful lov...
Introduction:Compassion is arguably central to palliative care. However, calls for the restoring of compassionate care suggest a need for greater understanding and promotion of compassion in practice. Drawing upon the Foucauldian concept 'Care of the Self', this review explored the literature relating...