Blood metabolome is commonly used in human studies to explore the associations of gut microbiota-derived metabolites with cardiometabolic diseases. Here, in a cohort of 1007 middle-aged and elderly adults with matched fecal metagenomic (149 species and 214 pathways) and paired fecal and blood targete...
Analysis of enteric microbiota function indirectly through the fecal metabolome has the potential to be an informative diagnostic tool. However, metabolomic analysis of feces is hampered by high concentrations of macromolecules such as proteins, fats, and fiber in samples. Three methods—ultrafiltration ...
Previously, we have reported that human milk-fed (HM) piglets had higher fecal Bacteroides abundance relative to a formula-fed group (MF), as well as a stronger immune response by which enhanced T cell proliferation in the mesenteric lymph nodes of HM-fed animals [11]. Gut and immune ...
to provide social media features and to analyse our traffic. We also share information about your use of our site with our social media, advertising and analytics partners who may combine it with other information that you’ve provided to them or that they’ve collected from your use of their...
Mouse models are widely used in preclinical FMT experiments, especially when transferring fecal microbiota from human donors, because it is possible to “humanize” the microbiota of these animals by mimicking the composition and profile of the donor [14]. ...