Pharmaceutical compositions and methods for the treatment of DENND1A.V2 related disorders, such as PCOS, are provided. In particular, humanized and mouse monoclonal antibodies specific for DENND1A.V2 and methods for using the same are provided.Application...
1. A method for eliciting an immune response against Borrelia in an individual in need thereof, comprising administering to said individual a chimeric protein comprising an epitope from an OspC type M loop 5 region consisting of SEQ ID NO: 19, an epitope from an OspC type D loop 5 region...
Bivalent multifunctional Aβ oligomerization inhibitors (BMAOIs) that target multiple risk factors involved in Alzheimer's disease are provided. The BMAOIs are useful for the treatment and/or prevention of Alzheimer's disease, as well as for diagnostic imaging of Aβ plaques in brain tissue. The...