Three patients had surgical resection and one underwent anterior callosotomy; these surgical treatments provided little or no improvement in seizure status. In nine patients with vagus nerve stimulator (VNS) implantation, limited improvement of seizures was noted in two patients and no improvement in ...
Although both ASD and SCHZ have strong inherited components, genetic risk seems to be distributed in hundreds of variants, each conferring low risk. The poor understanding of the genetics of ASD and SCHZ is a significant hurdle to developing effective treatments for these costly conditions. The ...
This work offers molecular biomarkers at the gene expression level and protein bases that could aid in a better understanding of molecular pathways, as well as potential pharmacological approaches and therapies for developing effective ASD treatments....
he is watching Disney Videos and crooning along in a sort of indistinct warbling. The only words he can pronounce are “Mama” and “Daddy. In the end, not everyone recovered the same way, even if they are using the same treatments. People’s mind works differently in every individual. ...
Experiment 3 showed that the two preexposure treatments did not differ in the extent to which they produced habituation of the neophobia evoked by X. Experiment 2 showed that conditioning to X proceeded more rapidly in subjects given preexposure to both AX and BX than in subjects preexposed to...
yet sophisticated accuracy therapies that often provide a less toxic alternative to standard salvage treatments. Notably, adoptive cellular therapy could be allo-HSCT-enabling or a therapeutic choice for patients in who transplantation features failed or is contraindicated. A great understanding of the co...
Table 3 Autism spectrum disorder interactome genes significantly altered by three or more shRNA treatments Full size table NextBio detection of related transcriptional profiles The Nextbio database allows for comparison of transcriptional profiles between datasets and transcriptional profiles for over 6,00...
The dose-response data of AgNPs on the leukocytes of cetaceans are invaluable for evaluating the adverse health effects in cetaceans and for proposing a conservation plan for marine mammals. Silver nanoparticles (AgNPs) have been extensively used in numerous commercial products including textiles, ...
d competition treatments, respectively, via Tukey tests. Complete coral-algal pairing is representative of such interactions. Moreover, the underlying mechanism for altered com- petitive ability has not been identified. Some algal competitive mechanisms have been recognised. Macroalgae may directly over...
These data provide novel insights into disease pathophysiology and identify possible new targets for therapeutic treatments of RTT. CONFLICT OF INTEREST The authors declare no conflict of interest. ACKNOWLEDGEMENTS We are grateful to A Bartolini for help with culture maintenance and differentiation. The ...