Background The aim was to evaluate the cost-utility of four common surgical treatment pathways for breast cancer: mastectomy, breast-conserving therapy (BCT), implant breast reconstruction (BR) and autologous-BR. Methods Patient-level healthcare consumption data and results of a large quality of ...
External beam radiation is the most toxic and expensive among common prostate cancer treatments over the long-term, a national registry study suggested. Although it's one of the most common treatments for Medicare patients with prostate cancer, external beam radiation had the highest 16-year cumulat...
Z-endoxifen, a potent derivative of the drug tamoxifen, could itself be a new treatment for the most common form of breast cancer in women with metastatic disease. This finding was reported from a clinical trial conducted by researchers at Mayo Clinic and the National Cancer Institute, and publ...
The authors set out to improve this evidence using patient-reported outcome measures in a large, cross-sectional study for different surgical breast cancer treatment options. Methods: Quality of life was assessed through the EQ-5D-5L, European Organization for Research and Treatment of Cancer ...
A rare variant of a protein present in nearly all human cells may hold the key to improving the effectiveness of breast cancer treatment, according to University of Manchester research funded by Bre…
Possible Beneficial Effects of N-Acetylcysteine for Treatment of Triple-Negative Breast Cancer-Youngjoo Kwon; Antioxidants (Basel); 2021 Jan 24;10(2):169. N-acetylcysteine and intestinal health: a focus on its mechanism of action;Yongqing Hou et al; Front Biosci (Landmark Ed), 2015 Jan 1;...
This paper shows IDO as a target of oncogenic signalling and highlights the potential of combining chemotherapy with IDO inhibition for the treatment of cancer. CAS PubMed Google Scholar Uyttenhove, C. et al. Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by ...
The second-most common type of breast cancer is a very different disease than the most common and appears to be a good candidate for a personalized approach to treatment, according to a multidisciplinary team led by scientists at the University of Pittsb
Despite advances in treatment, up to 30% of women eventually relapse and die of metastatic breast cancer. Liquid biopsy analysis of circulating cell-free DNA fragments in the patients’ blood can monitor clonality and evolving mutations as a surrogate for tumour biopsy. Next generation sequencing ...
Breast cancer has a strong heritable component, with approximately 15% of cases exhibiting a family history of the disease. Mutations in genes such as BRCA1, BRCA2 and TP53 lead to autosomal dominant inherited cancer susceptibility and confer a high life